Retinol-binding protein-4 is decreased in patients with preeclampsia in comparison with normal pregnant women

Hyun Joo Seol, Jae Won Kim, Hai Joong Kim

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Aims: The aim of this study was to investigate retinol-binding protein-4 (RBP4) levels in maternal and umbilical cord serum in patients in the third trimester of pregnancy with preeclam-psia in comparison to levels in normal pregnant women. Methods: The RBP4 levels in maternal and umbilical cord serum were measured and compared by enzyme-linked immunosorbent assay in 16 normal pregnant and 16 patients with preeclampsia. Results: Both maternal and umbilical cord serum RBP4 levels were significantly decreased in patients with preeclam-psia, as compared to normal pregnant women (maternal serum, median 168.0 μg/mL vs. 202.0 μg/mL, P<0.001; umbilical cord serum, median 147.9 μg/mL vs. 193.0 μg/mL, P<0.001). Preeclampsia was independently related to RBP4 levels of maternal and umbilical cord serum. Conclusion: Both maternal and umbilical cord serum RBP4 levels were lower in patients with preeclampsia than in normal pregnant women in the third trimester of pregnancy.

Original languageEnglish
Pages (from-to)287-289
Number of pages3
JournalJournal of Perinatal Medicine
Volume39
Issue number3
DOIs
Publication statusPublished - 2011 May 1

Keywords

  • Preeclampsia
  • Pregnancy
  • Retinol-binding protein-4

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Retinol-binding protein-4 is decreased in patients with preeclampsia in comparison with normal pregnant women'. Together they form a unique fingerprint.

  • Cite this