Retraction: Inhibition of AMP-activated protein kinase sensitizes cancer cells to cisplatin-induced apoptosis via hyper-induction of p53 (Journal of Biological Chemistry (2008) 283 (3731–3742) DOI: 10.1074/jbc.M704432200)

Hak Su Kim, Jin Taek Hwang, Hee Yun, Sung Gil Chi, Su Jae Lee, Insug Kang, Kyung Sik Yoon, Won Jae Choe, Sung Soo Kim, Joohun Ha

Research output: Contribution to journalComment/debate

Abstract

This article has been withdrawn by the authors. The a-actinin immunoblot from Fig. 1A from cells treated with 1-h cisplatin was duplicated in Fig. 3A. In Fig. 2A, lanes 2- 4 and lanes 7-9 of the ACC immunoblot were duplicated. The PARP immunoblot from Fig. 2F was duplicated in Fig. 5B. The last two lanes of the a-actinin immunoblot from Fig. 6B are duplicates. Lanes 1, 5, and 6 of the left ERK immunoblot were duplicated in Fig. 7A. Additionally, lanes 4 and 9 of the same immunoblot were also duplicated. In Fig. 9A, lanes 3 and 5 of the pAMPK immunoblot were duplicated. The Journal also raised questions regarding the ACC immunoblot in Fig. 5A, the ERK immunoblot in Fig. 7B, and the actinin immunoblot in Fig. 9A, which the withdrawing authors were not able to address. Because the original data are no longer available, the authors state that they repeated the above-mentioned experiments and obtained essentially identical results. The authors state that they have full confidence in the conclusions of this paper. The authors apologize to the readers.

Original languageEnglish
Pages (from-to)18015
Number of pages1
JournalJournal of Biological Chemistry
Volume293
Issue number46
DOIs
Publication statusPublished - 2018

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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