Rheological properties of culture broth of Acremonium chrysogenum M35 in baffled flasks with glass beads

Hwan Hyo Lee, Yoon Seok Song, Jeong Yong Lee, Hyun Wook Jung, Seung Wook Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effects of glass beads on the rheological properties of culture broths of Acremonium chrysogenum M35 grown in baffled flasks was investigated in this study. The addition of glass beads to cultures of A. chrysogenum M35 led to considerably higher levels of shear rheological properties such as shear stress versus shear rate, which are essential for controlling the performance of culture broths. The shear properties of culture broths of A. chrysogenum M35 evaluated in this study were also found to be better predicted by the power-law and the Herschel-Bulkley fluid models than by the Bingham plastic and the Casson fluid models. The consistency index (K) and the flow behavior index (n) data from the power-law fluid model for various culture broths clearly substantiated the usefulness of glass beads for effectively promoting the cell growth and cell differentiation, because they were directly affected by the morphological changes of A. chrysogenum M35 induced by the glass beads.

Original languageEnglish
Pages (from-to)51-58
Number of pages8
JournalKorea Australia Rheology Journal
Volume22
Issue number1
Publication statusPublished - 2010

Keywords

  • Acremonium chrysogenum
  • Glass beads
  • Morphology
  • Rheological models
  • Shear stress
  • Shear viscosity

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics

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