Rigiflex lithography-based nanodot arrays for localized surface plasmon resonance biosensors

Dong Kyu Park, Hye In Kim, Jun Pyo Kim, Je Seob Park, Su Yeon Lee, Seung Man Yang, Jeewon Lee, Chan Hwa Chung, Sang Jun Sim, Pil J. Yoo

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We present a facile and robust means of fabricating metallic nanodot arrays for localized surface plasmon resonance (LSPR) biosensors through the strategic coupling of a polymeric template prepared with rigiflex lithography and a subsequent metallization via electrodeposition. Rigiflex lithography provides the capability to realize large-scale nanosized features as well as process flexibility during contact molding. In addition, the electrodeposition process enables wet-based nanoscale metallization with high pattern fidelity and geometric controllability. Generated metallic nanodot arrays can be used as a general platform for LSPR biosensors via the sequential binding of chemicals and biomolecules. Extinction spectra of the corresponding LSPR signal are measured with UV-vis-NIR spectroscopy, from which the pattern size and shape dependence of LSPR are readily confirmed. The feasibility of a very sensitive biosensor is demonstrated by the targeted binding of human immunoglobulin G, yielding subnanomolar detection capability with high selectivity.

Original languageEnglish
Pages (from-to)6119-6126
Number of pages8
JournalLangmuir
Volume26
Issue number9
DOIs
Publication statusPublished - 2010 May 4

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ASJC Scopus subject areas

  • Electrochemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Materials Science(all)
  • Spectroscopy

Cite this

Park, D. K., Kim, H. I., Kim, J. P., Park, J. S., Lee, S. Y., Yang, S. M., Lee, J., Chung, C. H., Sim, S. J., & Yoo, P. J. (2010). Rigiflex lithography-based nanodot arrays for localized surface plasmon resonance biosensors. Langmuir, 26(9), 6119-6126. https://doi.org/10.1021/la100598v