Risk Factors and Oncologic Outcomes of Anastomosis Leakage after Laparoscopic Right Colectomy

Han Deok Kwak, Seon Hahn Kim, Dong Woo Kang, Se-Jin Baek, Jung-Myun Kwak, Jin Kim

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2 Citations (Scopus)

Abstract

Purpose: We estimated the incidence of anastomosis leakage and explore possible risk factors and oncologic outcomes following laparoscopic right-side colon resection among colon cancer patients. Materials and Methods: We retrospectively analyzed 423 patients who were diagnosed with appendiceal, cecal, ascending, or hepatic flexure colon cancer who underwent laparoscopic colonic resection and anastomosis between September 2006 and July 2014. We compared short-term and long-term outcomes between no-leakage and leakage groups. Results: There were 16 cases of right-side anastomosis leakage in a total 423 colon cancer cases (3.78%). The risk of leakage was increased in smokers (odds ratio=6.592, P=0.007) and with a longer operating time (odds ratio=1.024, P<0.001). There were no significant differences between the groups in local recurrence (P=0.106), overall survival (P=0.055), or cancer-specific survival (P=0.235). Conclusions: Smoking and long operating time are risk factors for right-side colon anastomosis. There were no significant differences in oncologic outcomes.

Original languageEnglish
Pages (from-to)440-444
Number of pages5
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Volume27
Issue number6
DOIs
Publication statusPublished - 2017 Jan 1

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Colectomy
Colonic Neoplasms
Colon
Odds Ratio
Survival
Smoking
Recurrence
Liver
Incidence
Neoplasms

Keywords

  • anastomosis leakage
  • laparoscopic resection
  • oncologic outcome
  • right-side colon cancer
  • risk factor

ASJC Scopus subject areas

  • Surgery

Cite this

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title = "Risk Factors and Oncologic Outcomes of Anastomosis Leakage after Laparoscopic Right Colectomy",
abstract = "Purpose: We estimated the incidence of anastomosis leakage and explore possible risk factors and oncologic outcomes following laparoscopic right-side colon resection among colon cancer patients. Materials and Methods: We retrospectively analyzed 423 patients who were diagnosed with appendiceal, cecal, ascending, or hepatic flexure colon cancer who underwent laparoscopic colonic resection and anastomosis between September 2006 and July 2014. We compared short-term and long-term outcomes between no-leakage and leakage groups. Results: There were 16 cases of right-side anastomosis leakage in a total 423 colon cancer cases (3.78{\%}). The risk of leakage was increased in smokers (odds ratio=6.592, P=0.007) and with a longer operating time (odds ratio=1.024, P<0.001). There were no significant differences between the groups in local recurrence (P=0.106), overall survival (P=0.055), or cancer-specific survival (P=0.235). Conclusions: Smoking and long operating time are risk factors for right-side colon anastomosis. There were no significant differences in oncologic outcomes.",
keywords = "anastomosis leakage, laparoscopic resection, oncologic outcome, right-side colon cancer, risk factor",
author = "Kwak, {Han Deok} and Kim, {Seon Hahn} and Kang, {Dong Woo} and Se-Jin Baek and Jung-Myun Kwak and Jin Kim",
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T1 - Risk Factors and Oncologic Outcomes of Anastomosis Leakage after Laparoscopic Right Colectomy

AU - Kwak, Han Deok

AU - Kim, Seon Hahn

AU - Kang, Dong Woo

AU - Baek, Se-Jin

AU - Kwak, Jung-Myun

AU - Kim, Jin

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Purpose: We estimated the incidence of anastomosis leakage and explore possible risk factors and oncologic outcomes following laparoscopic right-side colon resection among colon cancer patients. Materials and Methods: We retrospectively analyzed 423 patients who were diagnosed with appendiceal, cecal, ascending, or hepatic flexure colon cancer who underwent laparoscopic colonic resection and anastomosis between September 2006 and July 2014. We compared short-term and long-term outcomes between no-leakage and leakage groups. Results: There were 16 cases of right-side anastomosis leakage in a total 423 colon cancer cases (3.78%). The risk of leakage was increased in smokers (odds ratio=6.592, P=0.007) and with a longer operating time (odds ratio=1.024, P<0.001). There were no significant differences between the groups in local recurrence (P=0.106), overall survival (P=0.055), or cancer-specific survival (P=0.235). Conclusions: Smoking and long operating time are risk factors for right-side colon anastomosis. There were no significant differences in oncologic outcomes.

AB - Purpose: We estimated the incidence of anastomosis leakage and explore possible risk factors and oncologic outcomes following laparoscopic right-side colon resection among colon cancer patients. Materials and Methods: We retrospectively analyzed 423 patients who were diagnosed with appendiceal, cecal, ascending, or hepatic flexure colon cancer who underwent laparoscopic colonic resection and anastomosis between September 2006 and July 2014. We compared short-term and long-term outcomes between no-leakage and leakage groups. Results: There were 16 cases of right-side anastomosis leakage in a total 423 colon cancer cases (3.78%). The risk of leakage was increased in smokers (odds ratio=6.592, P=0.007) and with a longer operating time (odds ratio=1.024, P<0.001). There were no significant differences between the groups in local recurrence (P=0.106), overall survival (P=0.055), or cancer-specific survival (P=0.235). Conclusions: Smoking and long operating time are risk factors for right-side colon anastomosis. There were no significant differences in oncologic outcomes.

KW - anastomosis leakage

KW - laparoscopic resection

KW - oncologic outcome

KW - right-side colon cancer

KW - risk factor

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