Purpose: To identify the risk factors of pseudophakic retinal detachment after intraocular lens scleral fixation. Methods: We retrospectively reviewed the medical records of all patients who underwent intraocular lens implantation with scleral fixation and had at least 6 months of follow-up between January 2002 and December 2007. The risk factors for pseudophakic retinal detachment were investigated using various surgical variables. To find the significant predictors among the variables, we carried out binary logistic regression analysis with a backward selection method based on likelihood ratios. Results: Data from 395 eyes were analyzed. The pseudophakic retinal detachment rates were 8.46% (11 of the 130 eyes) in patients treated with pars plana vitrectomy (PPV) and 3.02% (8 of the 265 eyes) in patients treated without the PPV. Performing PPV (P = 0.023) was the only significant risk factor for pseudophakic retinal detachment after intraocular lens scleral fixation by logistic regression analysis. The odds ratio for PPV was 2.970 (95% confidence interval: 1.164-7.574). Conclusion: Performing PPV could be a risk factor of the pseudophakic retinal detachment after intraocular lens scleral fixation. If there is a choice, it should be decided carefully whether a PPV is performed at the time of intraocular lens scleral fixation.
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