Risk of adenomas with high-risk characteristics based on two previous colonoscopy

Kang Heum Suh, Ja Seol Koo, Jong Jin Hyun, Jungsoon Choi, Jang Soo Han, Seung Young Kim, Sung Woo Jung, Yoon Tae Jeen, Sang Woo Lee, Jai Hyun Choi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background and Aim: The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high-risk findings (HRF) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonoscopy. Methods: Among subjects who underwent screening colonoscopy during January 2002-December 2009, patients who underwent second surveillance colonoscopy before June 2012 were enrolled. "No adenoma" was defined as a hyperplastic polyp or no polyp, "low-risk findings (LRF)" as one or two small (<1cm) tubular adenomas, and "HRF" as advanced adenoma, cancer, or any sized multiple (≥3) adenomas. Results: Among enrolled 852 subjects, 65 (7.6%) had HRF at second surveillance colonoscopy. Multivariate analysis showed that HRF on second surveillance colonoscopy were associated with male and HRF on screening colonoscopy (all, P<0.01). In subjects with LRF on first surveillance colonoscopy, HRF on the screening colonoscopy significantly affected the detection of HRF on second surveillance colonoscopy (P<0.01). Patients with HRF on screening colonoscopy and LRF on the first surveillance colonoscopy had no different risk of HRF on second surveillance colonoscopy from those with HRF on first surveillance colonoscopy (P>0.05). Conclusions: The HRF on second surveillance are significantly associated with previous two colonoscopic results. In patients with LRF on first surveillance, screening colonoscopic findings should be considered to determine the optimal surveillance interval.

Original languageEnglish
Pages (from-to)1985-1990
Number of pages6
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume29
Issue number12
DOIs
Publication statusPublished - 2014 Jan 1

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Colonoscopy
Adenoma
Polyps

Keywords

  • High-risk findings
  • Polypectomy
  • Surveillance colonoscopy

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Risk of adenomas with high-risk characteristics based on two previous colonoscopy. / Suh, Kang Heum; Koo, Ja Seol; Hyun, Jong Jin; Choi, Jungsoon; Han, Jang Soo; Kim, Seung Young; Jung, Sung Woo; Jeen, Yoon Tae; Lee, Sang Woo; Choi, Jai Hyun.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 29, No. 12, 01.01.2014, p. 1985-1990.

Research output: Contribution to journalArticle

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abstract = "Background and Aim: The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high-risk findings (HRF) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonoscopy. Methods: Among subjects who underwent screening colonoscopy during January 2002-December 2009, patients who underwent second surveillance colonoscopy before June 2012 were enrolled. {"}No adenoma{"} was defined as a hyperplastic polyp or no polyp, {"}low-risk findings (LRF){"} as one or two small (<1cm) tubular adenomas, and {"}HRF{"} as advanced adenoma, cancer, or any sized multiple (≥3) adenomas. Results: Among enrolled 852 subjects, 65 (7.6{\%}) had HRF at second surveillance colonoscopy. Multivariate analysis showed that HRF on second surveillance colonoscopy were associated with male and HRF on screening colonoscopy (all, P<0.01). In subjects with LRF on first surveillance colonoscopy, HRF on the screening colonoscopy significantly affected the detection of HRF on second surveillance colonoscopy (P<0.01). Patients with HRF on screening colonoscopy and LRF on the first surveillance colonoscopy had no different risk of HRF on second surveillance colonoscopy from those with HRF on first surveillance colonoscopy (P>0.05). Conclusions: The HRF on second surveillance are significantly associated with previous two colonoscopic results. In patients with LRF on first surveillance, screening colonoscopic findings should be considered to determine the optimal surveillance interval.",
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AU - Hyun, Jong Jin

AU - Choi, Jungsoon

AU - Han, Jang Soo

AU - Kim, Seung Young

AU - Jung, Sung Woo

AU - Jeen, Yoon Tae

AU - Lee, Sang Woo

AU - Choi, Jai Hyun

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N2 - Background and Aim: The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high-risk findings (HRF) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonoscopy. Methods: Among subjects who underwent screening colonoscopy during January 2002-December 2009, patients who underwent second surveillance colonoscopy before June 2012 were enrolled. "No adenoma" was defined as a hyperplastic polyp or no polyp, "low-risk findings (LRF)" as one or two small (<1cm) tubular adenomas, and "HRF" as advanced adenoma, cancer, or any sized multiple (≥3) adenomas. Results: Among enrolled 852 subjects, 65 (7.6%) had HRF at second surveillance colonoscopy. Multivariate analysis showed that HRF on second surveillance colonoscopy were associated with male and HRF on screening colonoscopy (all, P<0.01). In subjects with LRF on first surveillance colonoscopy, HRF on the screening colonoscopy significantly affected the detection of HRF on second surveillance colonoscopy (P<0.01). Patients with HRF on screening colonoscopy and LRF on the first surveillance colonoscopy had no different risk of HRF on second surveillance colonoscopy from those with HRF on first surveillance colonoscopy (P>0.05). Conclusions: The HRF on second surveillance are significantly associated with previous two colonoscopic results. In patients with LRF on first surveillance, screening colonoscopic findings should be considered to determine the optimal surveillance interval.

AB - Background and Aim: The recommended intervals between surveillance colonoscopies are based on the most recent examination findings. However, whether the two previous colonoscopies affect second surveillance colonoscopic findings is not established. The aim of this study is to estimate the risk of obtaining high-risk findings (HRF) on the next surveillance colonoscopy using the results of two previous colonoscopies, and to estimate the appropriate time interval for the next surveillance colonoscopy. Methods: Among subjects who underwent screening colonoscopy during January 2002-December 2009, patients who underwent second surveillance colonoscopy before June 2012 were enrolled. "No adenoma" was defined as a hyperplastic polyp or no polyp, "low-risk findings (LRF)" as one or two small (<1cm) tubular adenomas, and "HRF" as advanced adenoma, cancer, or any sized multiple (≥3) adenomas. Results: Among enrolled 852 subjects, 65 (7.6%) had HRF at second surveillance colonoscopy. Multivariate analysis showed that HRF on second surveillance colonoscopy were associated with male and HRF on screening colonoscopy (all, P<0.01). In subjects with LRF on first surveillance colonoscopy, HRF on the screening colonoscopy significantly affected the detection of HRF on second surveillance colonoscopy (P<0.01). Patients with HRF on screening colonoscopy and LRF on the first surveillance colonoscopy had no different risk of HRF on second surveillance colonoscopy from those with HRF on first surveillance colonoscopy (P>0.05). Conclusions: The HRF on second surveillance are significantly associated with previous two colonoscopic results. In patients with LRF on first surveillance, screening colonoscopic findings should be considered to determine the optimal surveillance interval.

KW - High-risk findings

KW - Polypectomy

KW - Surveillance colonoscopy

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