Abstract
Background and Purpose: Cardiac multidetector computed tomography (MDCT) is less dependent upon the patient's condition and may be valuable in the diagnosis of embolic sources when the patient's cooperation is limited due to a neurologic deficit. However, its role has never been validated in acute stroke patients whose stroke mechanism is assumed to be embolic. Methods: Consecutive patients who were admitted with acute ischemic stroke from May 1, 2007 to November 30, 2007 were included in this study. Inclusion criteria were (1) any cardiac evidence of high-risk embolic sources for cerebral embolism, or (2) radiological or (3) clinical evidence of embolic stroke. All patients underwent transthoracic echocardiography first, and then cardiac MDCT or transesophageal echocardiography (TEE) was attempted, if possible. The results and feasibility of cardiac MDCT and TEE were compared. Results: One hundred and forty-three patients met the inclusion criteria. Cardiac MDCT was performed in 124 patients (86.7%), TEE in 83 patients (57.3%), whereas 75 patients (52.4%) underwent both studies. Renal insufficiency for cardiac MDCT and lack of cooperation for TEE were found to be the most impeding factors. Among the patients with both evaluations, cardiac MDCT identified a high-risk intracardiac embolic source in 8 and an extracardiac source in 20, while TEE found an intracardiac source in 1 and an extracardiac source in 7. Statistically significant differences were found with respect to detecting cardioembolic sources and high-risk aortic atheroma. Conclusions: Cardiac MDCT is a feasible and accurate diagnostic tool for embolic sources in an acute stroke setting.
| Original language | English |
|---|---|
| Pages (from-to) | 313-320 |
| Number of pages | 8 |
| Journal | Cerebrovascular Diseases |
| Volume | 29 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2010 Mar 1 |
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Keywords
- Acute ischemic stroke
- Cardiac multidetector computed tomography
- Transesophageal echocardiography
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Cardiology and Cardiovascular Medicine
Cite this
Role of cardiac multidetector computed tomography in acute ischemic stroke : A preliminary report. / Ko, Sang Bae; Choi, Sang Il; Chun, Eun Ju; Ko, Youngchai; Park, Jung Hyun; Lee, Sook Jin; Lee, Juneyoung; Han, Moon Ku; Bae, Hee Joon.
In: Cerebrovascular Diseases, Vol. 29, No. 4, 01.03.2010, p. 313-320.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of cardiac multidetector computed tomography in acute ischemic stroke
T2 - A preliminary report
AU - Ko, Sang Bae
AU - Choi, Sang Il
AU - Chun, Eun Ju
AU - Ko, Youngchai
AU - Park, Jung Hyun
AU - Lee, Sook Jin
AU - Lee, Juneyoung
AU - Han, Moon Ku
AU - Bae, Hee Joon
PY - 2010/3/1
Y1 - 2010/3/1
N2 - Background and Purpose: Cardiac multidetector computed tomography (MDCT) is less dependent upon the patient's condition and may be valuable in the diagnosis of embolic sources when the patient's cooperation is limited due to a neurologic deficit. However, its role has never been validated in acute stroke patients whose stroke mechanism is assumed to be embolic. Methods: Consecutive patients who were admitted with acute ischemic stroke from May 1, 2007 to November 30, 2007 were included in this study. Inclusion criteria were (1) any cardiac evidence of high-risk embolic sources for cerebral embolism, or (2) radiological or (3) clinical evidence of embolic stroke. All patients underwent transthoracic echocardiography first, and then cardiac MDCT or transesophageal echocardiography (TEE) was attempted, if possible. The results and feasibility of cardiac MDCT and TEE were compared. Results: One hundred and forty-three patients met the inclusion criteria. Cardiac MDCT was performed in 124 patients (86.7%), TEE in 83 patients (57.3%), whereas 75 patients (52.4%) underwent both studies. Renal insufficiency for cardiac MDCT and lack of cooperation for TEE were found to be the most impeding factors. Among the patients with both evaluations, cardiac MDCT identified a high-risk intracardiac embolic source in 8 and an extracardiac source in 20, while TEE found an intracardiac source in 1 and an extracardiac source in 7. Statistically significant differences were found with respect to detecting cardioembolic sources and high-risk aortic atheroma. Conclusions: Cardiac MDCT is a feasible and accurate diagnostic tool for embolic sources in an acute stroke setting.
AB - Background and Purpose: Cardiac multidetector computed tomography (MDCT) is less dependent upon the patient's condition and may be valuable in the diagnosis of embolic sources when the patient's cooperation is limited due to a neurologic deficit. However, its role has never been validated in acute stroke patients whose stroke mechanism is assumed to be embolic. Methods: Consecutive patients who were admitted with acute ischemic stroke from May 1, 2007 to November 30, 2007 were included in this study. Inclusion criteria were (1) any cardiac evidence of high-risk embolic sources for cerebral embolism, or (2) radiological or (3) clinical evidence of embolic stroke. All patients underwent transthoracic echocardiography first, and then cardiac MDCT or transesophageal echocardiography (TEE) was attempted, if possible. The results and feasibility of cardiac MDCT and TEE were compared. Results: One hundred and forty-three patients met the inclusion criteria. Cardiac MDCT was performed in 124 patients (86.7%), TEE in 83 patients (57.3%), whereas 75 patients (52.4%) underwent both studies. Renal insufficiency for cardiac MDCT and lack of cooperation for TEE were found to be the most impeding factors. Among the patients with both evaluations, cardiac MDCT identified a high-risk intracardiac embolic source in 8 and an extracardiac source in 20, while TEE found an intracardiac source in 1 and an extracardiac source in 7. Statistically significant differences were found with respect to detecting cardioembolic sources and high-risk aortic atheroma. Conclusions: Cardiac MDCT is a feasible and accurate diagnostic tool for embolic sources in an acute stroke setting.
KW - Acute ischemic stroke
KW - Cardiac multidetector computed tomography
KW - Transesophageal echocardiography
UR - http://www.scopus.com/inward/record.url?scp=75549084152&partnerID=8YFLogxK
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U2 - 10.1159/000278926
DO - 10.1159/000278926
M3 - Article
VL - 29
SP - 313
EP - 320
JO - Cerebrovascular Diseases
JF - Cerebrovascular Diseases
SN - 1015-9770
IS - 4
ER -