Role of Inflammation in Psychiatric Disorders

Sang Won Jeon, Ho kyoung Yoon, Yong Ku Kim

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2 Citations (Scopus)

    Abstract

    Psychiatric disorders are too multifactorial to be defined as a primarily inflammatory disorder, and increased inflammatory response is not specific to mental disorder only. Numerous factors are involved in neuroinflammation, and there also are many confounding variables, making it difficult to obtain consistent outcomes. Therefore, it is necessary to specify genetic, physiological, and epidemiological attributes of particular population groups vulnerable to inflammatory response as well as the disease subtypes. As of now, definitive inflammatory markers for psychiatric disorders have not been identified, but they could be very useful in patients with minimal vulnerability. In addition, it is possible to use inflammatory markers as depression biomarkers in subtypes of depression, which can serve as bases to develop medications to treat the disorder.

    Original languageEnglish
    Title of host publicationAdvances in Experimental Medicine and Biology
    PublisherSpringer New York LLC
    Pages491-501
    Number of pages11
    DOIs
    Publication statusPublished - 2019

    Publication series

    NameAdvances in Experimental Medicine and Biology
    Volume1192
    ISSN (Print)0065-2598
    ISSN (Electronic)2214-8019

    Keywords

    • Cytokine
    • Depression
    • Inflammation
    • Medication
    • Neuroinflammation
    • Psychiatric disorder

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)

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