Role of Inflammation in Psychiatric Disorders

Sang Won Jeon, Ho kyoung Yoon, Yong Ku Kim

Research output: Chapter in Book/Report/Conference proceedingChapter


Psychiatric disorders are too multifactorial to be defined as a primarily inflammatory disorder, and increased inflammatory response is not specific to mental disorder only. Numerous factors are involved in neuroinflammation, and there also are many confounding variables, making it difficult to obtain consistent outcomes. Therefore, it is necessary to specify genetic, physiological, and epidemiological attributes of particular population groups vulnerable to inflammatory response as well as the disease subtypes. As of now, definitive inflammatory markers for psychiatric disorders have not been identified, but they could be very useful in patients with minimal vulnerability. In addition, it is possible to use inflammatory markers as depression biomarkers in subtypes of depression, which can serve as bases to develop medications to treat the disorder.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages11
Publication statusPublished - 2019 Jan 1

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • Cytokine
  • Depression
  • Inflammation
  • Medication
  • Neuroinflammation
  • Psychiatric disorder

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Jeon, S. W., Yoon, H. K., & Kim, Y. K. (2019). Role of Inflammation in Psychiatric Disorders. In Advances in Experimental Medicine and Biology (pp. 491-501). (Advances in Experimental Medicine and Biology; Vol. 1192). Springer New York LLC.