Rome foundation Asian working team report: Real world treatment experience of Asian patients with functional bowel disorders

Lishou Xiong, Xiaorong Gong, Kewin Tien Ho Siah, Nitesh Pratap, Uday Chand Ghoshal, Murdani Abdullah, Ari Fahrial Syam, Young-Tae Bak, Myung Gyu Choi, Ching Liang Lu, Sutep Gonlachanvit, Andrew Seng Boon Chua, Kuck Meng Chong, Jane D. Ricaforte-Campos, Quan Shi, Xiaohua Hou, William E. Whitehead, Kok Ann Gwee, Minhu Chen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background and Aim: Information on real world treatment experiences of patients with functional bowel disorders is lacking from Asia. This study aimed to describe the medication exposure and treatment satisfaction of patients presenting to gastroenterology clinics across a sampling of Asian cities. Methods: From March 2011 to October 2013, adult patients presenting to hospital-based gastroenterology outpatient clinics in 11 cities across Asia, who fulfilled screening criteria for any functional gastrointestinal disorder, were asked to complete a validated culturally adapted translation of the Rome III diagnostic questionnaire, a checklist of medications received in the preceding 3 months and questions on treatment satisfaction. Results: A total of 1376 patients (female 755, male 621, 41.36 ± 13.25 years) comprising irritable bowel (621, 45.1%), unspecified functional bowel disorder (372, 27.8%), functional constipation (202, 14.7%), functional bloating (144, 10.5%), and functional diarrhea (56, 4.1%) completed the study. Of 1105 patients with a previous consultation, 509 (46.1%) were dissatisfied with their treatment, with ineffective treatment being the commonest reason. Satisfaction with previous consultation was lowest by diagnosis for functional constipation (29.2%), and the most bothersome symptom was straining (37.5%). Of 1046 patients who had taken medications for their gastrointestinal symptoms in the last 3 months, 793 (75.8%) had received two or more drugs. For irritable bowel syndrome patients, treatment with proton pump inhibitors and antispasmodics was recorded in 57% and 31%, with overlapping epigastric pain and heartburn predicting proton pump inhibitors use. Conclusions: More attention should be given to treatment gaps with regards to possible under-treatment with antispasmodics in irritable bowel syndrome and to critically evaluating the efficacy of constipation management.

Original languageEnglish
Pages (from-to)1450-1456
Number of pages7
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume32
Issue number8
DOIs
Publication statusPublished - 2017 Aug 1

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Constipation
Parasympatholytics
Irritable Bowel Syndrome
Proton Pump Inhibitors
Gastroenterology
Therapeutics
Referral and Consultation
Heartburn
Gastrointestinal Diseases
Ambulatory Care Facilities
Checklist
Patient Satisfaction
Diarrhea
Pain
Pharmaceutical Preparations

Keywords

  • Asia
  • constipation
  • functional GI disorders
  • irritable bowel
  • treatment

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Rome foundation Asian working team report : Real world treatment experience of Asian patients with functional bowel disorders. / Xiong, Lishou; Gong, Xiaorong; Siah, Kewin Tien Ho; Pratap, Nitesh; Ghoshal, Uday Chand; Abdullah, Murdani; Syam, Ari Fahrial; Bak, Young-Tae; Choi, Myung Gyu; Lu, Ching Liang; Gonlachanvit, Sutep; Chua, Andrew Seng Boon; Chong, Kuck Meng; Ricaforte-Campos, Jane D.; Shi, Quan; Hou, Xiaohua; Whitehead, William E.; Gwee, Kok Ann; Chen, Minhu.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 32, No. 8, 01.08.2017, p. 1450-1456.

Research output: Contribution to journalArticle

Xiong, L, Gong, X, Siah, KTH, Pratap, N, Ghoshal, UC, Abdullah, M, Syam, AF, Bak, Y-T, Choi, MG, Lu, CL, Gonlachanvit, S, Chua, ASB, Chong, KM, Ricaforte-Campos, JD, Shi, Q, Hou, X, Whitehead, WE, Gwee, KA & Chen, M 2017, 'Rome foundation Asian working team report: Real world treatment experience of Asian patients with functional bowel disorders', Journal of Gastroenterology and Hepatology (Australia), vol. 32, no. 8, pp. 1450-1456. https://doi.org/10.1111/jgh.13730
Xiong, Lishou ; Gong, Xiaorong ; Siah, Kewin Tien Ho ; Pratap, Nitesh ; Ghoshal, Uday Chand ; Abdullah, Murdani ; Syam, Ari Fahrial ; Bak, Young-Tae ; Choi, Myung Gyu ; Lu, Ching Liang ; Gonlachanvit, Sutep ; Chua, Andrew Seng Boon ; Chong, Kuck Meng ; Ricaforte-Campos, Jane D. ; Shi, Quan ; Hou, Xiaohua ; Whitehead, William E. ; Gwee, Kok Ann ; Chen, Minhu. / Rome foundation Asian working team report : Real world treatment experience of Asian patients with functional bowel disorders. In: Journal of Gastroenterology and Hepatology (Australia). 2017 ; Vol. 32, No. 8. pp. 1450-1456.
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abstract = "Background and Aim: Information on real world treatment experiences of patients with functional bowel disorders is lacking from Asia. This study aimed to describe the medication exposure and treatment satisfaction of patients presenting to gastroenterology clinics across a sampling of Asian cities. Methods: From March 2011 to October 2013, adult patients presenting to hospital-based gastroenterology outpatient clinics in 11 cities across Asia, who fulfilled screening criteria for any functional gastrointestinal disorder, were asked to complete a validated culturally adapted translation of the Rome III diagnostic questionnaire, a checklist of medications received in the preceding 3 months and questions on treatment satisfaction. Results: A total of 1376 patients (female 755, male 621, 41.36 ± 13.25 years) comprising irritable bowel (621, 45.1{\%}), unspecified functional bowel disorder (372, 27.8{\%}), functional constipation (202, 14.7{\%}), functional bloating (144, 10.5{\%}), and functional diarrhea (56, 4.1{\%}) completed the study. Of 1105 patients with a previous consultation, 509 (46.1{\%}) were dissatisfied with their treatment, with ineffective treatment being the commonest reason. Satisfaction with previous consultation was lowest by diagnosis for functional constipation (29.2{\%}), and the most bothersome symptom was straining (37.5{\%}). Of 1046 patients who had taken medications for their gastrointestinal symptoms in the last 3 months, 793 (75.8{\%}) had received two or more drugs. For irritable bowel syndrome patients, treatment with proton pump inhibitors and antispasmodics was recorded in 57{\%} and 31{\%}, with overlapping epigastric pain and heartburn predicting proton pump inhibitors use. Conclusions: More attention should be given to treatment gaps with regards to possible under-treatment with antispasmodics in irritable bowel syndrome and to critically evaluating the efficacy of constipation management.",
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