Safety, feasibility, and short-term outcomes in 588 patients undergoing minimally invasive ileal pouch-anal anastomosis: a single-institution experience

Se-Jin Baek, E. J. Dozois, K. L. Mathis, A. L. Lightner, S. Y. Boostrom, R. R. Cima, J. H. Pemberton, D. W. Larson

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose: A laparoscopic approach to proctocolectomy and ileal pouch-anal anastomosis (IPAA) in patients with chronic ulcerative colitis and familial adenomatous polyposis has grown in popularity secondary to reports of small series demonstrating short-term patient benefits. Limited data exist in large numbers of patients undergoing laparoscopic ileal pouch-anal anastomosis (L-IPAA). We aimed to analyze surgical outcomes in a large cohort of patients undergoing L-IPAA. Methods: From a prospectively maintained surgical database, 30-day surgical outcome data were reviewed for all L-IPAA performed for chronic ulcerative colitis and familial adenomatous polyposis from 1999 to 2012. Demographics, operative approach, and operative and postoperative complications were analyzed. Results: A total of 588 L-IPAA ileal pouch-anal anastomoses were performed predominantly for chronic ulcerative colitis (93.9 %). The mean age was 36.2 years, and 54.3 % were male, with a mean BMI of 24.1 kg/m2. Three-stage operations were performed in 17.7 %. The mean operating time of the patients excluding 3-stage operation was 269.4 min. Minimally invasive techniques included hand-assist in 55 % and straight laparoscopy in 45 %. Conversion to open occurred in 8.8 %. Median length of stay was 5 days. There was no mortality. Complications occurred in 36.9 % of patients: Clavien grade I (17.5 %), grade II (72.8 %), and grade III (9.7 %). Analysis of the grouped data over time demonstrated a statistically significant reduction in operative time (p < 0.001) and an increase in the ratio of hand-assisted over straight laparoscopy (p = 0.001). Conclusions: Minimally invasive IPAA performed using either a laparoscopic or hand-assisted technique is safe, can be performed with low conversion rates, and confers beneficial perioperative outcomes.

Original languageEnglish
Pages (from-to)369-374
Number of pages6
JournalTechniques in Coloproctology
Volume20
Issue number6
DOIs
Publication statusPublished - 2016 Jun 1
Externally publishedYes

Fingerprint

Colonic Pouches
Safety
Ulcerative Colitis
Adenomatous Polyposis Coli
Hand
Laparoscopy
Operative Time
Length of Stay
Demography
Databases
Mortality

Keywords

  • IPAA
  • Laparoscopy
  • Postoperative complication

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Safety, feasibility, and short-term outcomes in 588 patients undergoing minimally invasive ileal pouch-anal anastomosis : a single-institution experience. / Baek, Se-Jin; Dozois, E. J.; Mathis, K. L.; Lightner, A. L.; Boostrom, S. Y.; Cima, R. R.; Pemberton, J. H.; Larson, D. W.

In: Techniques in Coloproctology, Vol. 20, No. 6, 01.06.2016, p. 369-374.

Research output: Contribution to journalArticle

Baek, Se-Jin ; Dozois, E. J. ; Mathis, K. L. ; Lightner, A. L. ; Boostrom, S. Y. ; Cima, R. R. ; Pemberton, J. H. ; Larson, D. W. / Safety, feasibility, and short-term outcomes in 588 patients undergoing minimally invasive ileal pouch-anal anastomosis : a single-institution experience. In: Techniques in Coloproctology. 2016 ; Vol. 20, No. 6. pp. 369-374.
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abstract = "Purpose: A laparoscopic approach to proctocolectomy and ileal pouch-anal anastomosis (IPAA) in patients with chronic ulcerative colitis and familial adenomatous polyposis has grown in popularity secondary to reports of small series demonstrating short-term patient benefits. Limited data exist in large numbers of patients undergoing laparoscopic ileal pouch-anal anastomosis (L-IPAA). We aimed to analyze surgical outcomes in a large cohort of patients undergoing L-IPAA. Methods: From a prospectively maintained surgical database, 30-day surgical outcome data were reviewed for all L-IPAA performed for chronic ulcerative colitis and familial adenomatous polyposis from 1999 to 2012. Demographics, operative approach, and operative and postoperative complications were analyzed. Results: A total of 588 L-IPAA ileal pouch-anal anastomoses were performed predominantly for chronic ulcerative colitis (93.9 {\%}). The mean age was 36.2 years, and 54.3 {\%} were male, with a mean BMI of 24.1 kg/m2. Three-stage operations were performed in 17.7 {\%}. The mean operating time of the patients excluding 3-stage operation was 269.4 min. Minimally invasive techniques included hand-assist in 55 {\%} and straight laparoscopy in 45 {\%}. Conversion to open occurred in 8.8 {\%}. Median length of stay was 5 days. There was no mortality. Complications occurred in 36.9 {\%} of patients: Clavien grade I (17.5 {\%}), grade II (72.8 {\%}), and grade III (9.7 {\%}). Analysis of the grouped data over time demonstrated a statistically significant reduction in operative time (p < 0.001) and an increase in the ratio of hand-assisted over straight laparoscopy (p = 0.001). Conclusions: Minimally invasive IPAA performed using either a laparoscopic or hand-assisted technique is safe, can be performed with low conversion rates, and confers beneficial perioperative outcomes.",
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AU - Baek, Se-Jin

AU - Dozois, E. J.

AU - Mathis, K. L.

AU - Lightner, A. L.

AU - Boostrom, S. Y.

AU - Cima, R. R.

AU - Pemberton, J. H.

AU - Larson, D. W.

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