Safety of LigaSure in recurrent laryngeal nerve dissection-porcine model using continuous monitoring

Gianlorenzo Dionigi, Feng Yu Chiang, Hoon Yub Kim, Gregory W. Randolph, Alberto Mangano, Pi Ying Chang, I. Cheng Lu, Yi Chu Lin, Hui Chun Chen, Che Wei Wu

    Research output: Contribution to journalArticlepeer-review

    15 Citations (Scopus)

    Abstract

    Objectives/Hypothesis: This study investigated recurrent laryngeal nerve (RLN) real-time electromyography (EMG) data to define optimal safety parameters of the LigaSure Small Jaw (LSJ) instrument during thyroidectomy. Study Design: Prospective animal model. Methods: Dynamic EMG tracings were recorded from 32 RLNs (16 piglets) during various applications of LSJ around using continuous electrophysiologic monitoring. At varying distances from the RLN, the LSJ was activated (activation study). The LSJ was also applied to the RLN at timed intervals after activation and after a cooling maneuver through placement on the sternocleidomastoid muscle (cooling study). Results: In the activation study, there was no adverse EMG event at 2 to 5 mm distance (16 RLNs, 96 tests). In the cooling study, there was no adverse EMG event after 2-second cooling time (16 RLNs, 96 tests) or after the LSJ cooling maneuver on the surrounding muscle before reaching the RLNs (8 RLNs, 24 tests). Conclusion: Based on EMG functional assessment, the safe distance for LSJ activation was 2 mm. Further LSJ–RLN contact was safe if the LSJ was cooled for more than 2 seconds or cooled by touch muscle maneuver. The LSJ should be used with these distance and time parameters in mind to avoid RLN injury. Level of Evidence: N/A. Laryngoscope, 127:1724–1729, 2017.

    Original languageEnglish
    Pages (from-to)1724-1729
    Number of pages6
    JournalLaryngoscope
    Volume127
    Issue number7
    DOIs
    Publication statusPublished - 2017 Jul

    Keywords

    • LigaSure
    • Recurrent laryngeal nerve
    • electromyography
    • intraoperative neuromonitoring
    • thyroidectomy

    ASJC Scopus subject areas

    • Otorhinolaryngology

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