Salt concentration-induced dehybridisation of DNA-gold nanoparticle conjugate assemblies for diagnostic applications

Ju Hwan Oh, Jae-Seung Lee

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We present the cooperative dehybridisation of DNA-gold nanoparticle conjugate (DNA-AuNP) assemblies induced by reduced salt concentration ([salt]), which can be precisely controlled by various conditions. The detection of Ag+ based upon the [salt]-induced dehybridisation of DNA-AuNP assemblies is five times more sensitive than that achieved under conventional thermal melting conditions.

Original languageEnglish
Pages (from-to)6382-6384
Number of pages3
JournalChemical Communications
Volume46
Issue number34
DOIs
Publication statusPublished - 2010 Sep 14

Fingerprint

Gold
Nanoparticles
DNA
Salts
Freezing
Melting
Hot Temperature

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Salt concentration-induced dehybridisation of DNA-gold nanoparticle conjugate assemblies for diagnostic applications. / Oh, Ju Hwan; Lee, Jae-Seung.

In: Chemical Communications, Vol. 46, No. 34, 14.09.2010, p. 6382-6384.

Research output: Contribution to journalArticle

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