Salt concentration-induced dehybridisation of DNA-gold nanoparticle conjugate assemblies for diagnostic applications

Ju Hwan Oh, Jae Seung Lee

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We present the cooperative dehybridisation of DNA-gold nanoparticle conjugate (DNA-AuNP) assemblies induced by reduced salt concentration ([salt]), which can be precisely controlled by various conditions. The detection of Ag+ based upon the [salt]-induced dehybridisation of DNA-AuNP assemblies is five times more sensitive than that achieved under conventional thermal melting conditions.

Original languageEnglish
Pages (from-to)6382-6384
Number of pages3
JournalChemical Communications
Volume46
Issue number34
DOIs
Publication statusPublished - 2010 Sep 14

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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