Sampling polyhexamethylene guanidine aerosols using Eosin Y-coated glass beads

Sang Hyun Choi, Seon Kyung Park, Hyun Joong Kang, Kyuhong Lee, Jung-Hwan Kwon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Fatalities caused by the use of polyhexamethylene guanidine (PHMG), a general-purpose chemical germicide used as a humidifier disinfectant in Korea, have raised concerns about exposure to biocide aerosols in indoor environments. A sampler capable of accumulating PHMG from aqueous aerosols was developed as an alternative to low-volume air samplers. This sampler was prepared by placing glass beads coated with 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate (Eosin Y) in a custom-made plastic holder. Passive sampling rates, measured in a bench-top exposure chamber at two different aqueous PHMG aerosol generation rates, were found to be independent of the experimental conditions. This suggests that the capacity of the sampler to accumulate the PHMG aerosol was sufficient for the sampling duration tested. However, the passive sampling rate was 7.6 × 10<sup>-6</sup>m<sup>3</sup>/h for the sampler area of 22 cm<sup>2</sup>. This rate is lower than the typical human breathing rate and inadequate for quantitative instrumental analyses at low concentrations in indoor air. A 30-fold enhancement of the sampling rate was achieved by forced convection using a commercial battery-operated fan at ≥2000 rpm. With this accelerated sampling rate, the sampler could be used to monitor time-integrated concentrations of PHMG aerosols in the air.

Original languageEnglish
Pages (from-to)1819-1823
Number of pages5
JournalBulletin of the Korean Chemical Society
Volume36
Issue number7
DOIs
Publication statusPublished - 2015 Jul 1

Fingerprint

Guanidine
Eosine Yellowish-(YS)
Aerosols
Sampling
Glass
Disinfectants
Air
Benzoates
Forced convection
Fans
Plastics

Keywords

  • Colorimetry
  • Exposure assessment
  • Indoor air
  • Passive samplers

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Sampling polyhexamethylene guanidine aerosols using Eosin Y-coated glass beads. / Choi, Sang Hyun; Park, Seon Kyung; Kang, Hyun Joong; Lee, Kyuhong; Kwon, Jung-Hwan.

In: Bulletin of the Korean Chemical Society, Vol. 36, No. 7, 01.07.2015, p. 1819-1823.

Research output: Contribution to journalArticle

Choi, Sang Hyun ; Park, Seon Kyung ; Kang, Hyun Joong ; Lee, Kyuhong ; Kwon, Jung-Hwan. / Sampling polyhexamethylene guanidine aerosols using Eosin Y-coated glass beads. In: Bulletin of the Korean Chemical Society. 2015 ; Vol. 36, No. 7. pp. 1819-1823.
@article{5b1cc1ee6bc747bebfb72189a7f7888b,
title = "Sampling polyhexamethylene guanidine aerosols using Eosin Y-coated glass beads",
abstract = "Fatalities caused by the use of polyhexamethylene guanidine (PHMG), a general-purpose chemical germicide used as a humidifier disinfectant in Korea, have raised concerns about exposure to biocide aerosols in indoor environments. A sampler capable of accumulating PHMG from aqueous aerosols was developed as an alternative to low-volume air samplers. This sampler was prepared by placing glass beads coated with 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate (Eosin Y) in a custom-made plastic holder. Passive sampling rates, measured in a bench-top exposure chamber at two different aqueous PHMG aerosol generation rates, were found to be independent of the experimental conditions. This suggests that the capacity of the sampler to accumulate the PHMG aerosol was sufficient for the sampling duration tested. However, the passive sampling rate was 7.6 × 10-6m3/h for the sampler area of 22 cm2. This rate is lower than the typical human breathing rate and inadequate for quantitative instrumental analyses at low concentrations in indoor air. A 30-fold enhancement of the sampling rate was achieved by forced convection using a commercial battery-operated fan at ≥2000 rpm. With this accelerated sampling rate, the sampler could be used to monitor time-integrated concentrations of PHMG aerosols in the air.",
keywords = "Colorimetry, Exposure assessment, Indoor air, Passive samplers",
author = "Choi, {Sang Hyun} and Park, {Seon Kyung} and Kang, {Hyun Joong} and Kyuhong Lee and Jung-Hwan Kwon",
year = "2015",
month = "7",
day = "1",
doi = "10.1002/bkcs.10345",
language = "English",
volume = "36",
pages = "1819--1823",
journal = "Bulletin of the Korean Chemical Society",
issn = "0253-2964",
publisher = "Wiley-Blackwell",
number = "7",

}

TY - JOUR

T1 - Sampling polyhexamethylene guanidine aerosols using Eosin Y-coated glass beads

AU - Choi, Sang Hyun

AU - Park, Seon Kyung

AU - Kang, Hyun Joong

AU - Lee, Kyuhong

AU - Kwon, Jung-Hwan

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Fatalities caused by the use of polyhexamethylene guanidine (PHMG), a general-purpose chemical germicide used as a humidifier disinfectant in Korea, have raised concerns about exposure to biocide aerosols in indoor environments. A sampler capable of accumulating PHMG from aqueous aerosols was developed as an alternative to low-volume air samplers. This sampler was prepared by placing glass beads coated with 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate (Eosin Y) in a custom-made plastic holder. Passive sampling rates, measured in a bench-top exposure chamber at two different aqueous PHMG aerosol generation rates, were found to be independent of the experimental conditions. This suggests that the capacity of the sampler to accumulate the PHMG aerosol was sufficient for the sampling duration tested. However, the passive sampling rate was 7.6 × 10-6m3/h for the sampler area of 22 cm2. This rate is lower than the typical human breathing rate and inadequate for quantitative instrumental analyses at low concentrations in indoor air. A 30-fold enhancement of the sampling rate was achieved by forced convection using a commercial battery-operated fan at ≥2000 rpm. With this accelerated sampling rate, the sampler could be used to monitor time-integrated concentrations of PHMG aerosols in the air.

AB - Fatalities caused by the use of polyhexamethylene guanidine (PHMG), a general-purpose chemical germicide used as a humidifier disinfectant in Korea, have raised concerns about exposure to biocide aerosols in indoor environments. A sampler capable of accumulating PHMG from aqueous aerosols was developed as an alternative to low-volume air samplers. This sampler was prepared by placing glass beads coated with 2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate (Eosin Y) in a custom-made plastic holder. Passive sampling rates, measured in a bench-top exposure chamber at two different aqueous PHMG aerosol generation rates, were found to be independent of the experimental conditions. This suggests that the capacity of the sampler to accumulate the PHMG aerosol was sufficient for the sampling duration tested. However, the passive sampling rate was 7.6 × 10-6m3/h for the sampler area of 22 cm2. This rate is lower than the typical human breathing rate and inadequate for quantitative instrumental analyses at low concentrations in indoor air. A 30-fold enhancement of the sampling rate was achieved by forced convection using a commercial battery-operated fan at ≥2000 rpm. With this accelerated sampling rate, the sampler could be used to monitor time-integrated concentrations of PHMG aerosols in the air.

KW - Colorimetry

KW - Exposure assessment

KW - Indoor air

KW - Passive samplers

UR - http://www.scopus.com/inward/record.url?scp=84936748061&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84936748061&partnerID=8YFLogxK

U2 - 10.1002/bkcs.10345

DO - 10.1002/bkcs.10345

M3 - Article

AN - SCOPUS:84936748061

VL - 36

SP - 1819

EP - 1823

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

SN - 0253-2964

IS - 7

ER -