Screening for normal cognition, mild cognitive impairment, and dementia with the Korean dementia screening questionnaire

Sun Ju Lee, Jung Hoon Han, Jung Won Hwang, Jong Woo Paik, Changsu Han, Moon Ho Park

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective The Korean Dementia Screening Questionnaire (KDSQ) is an informant-based instrument used to screen for cognitive dysfunction. However, its ability to only dichotomously discriminate between dementia and normal cognition has been previously investigated. This study investigated the ability of the KDSQ to classify not only dichotomous but also multiple stages of cognitive dysfunction. Methods We examined 582 participants. Receiver operating characteristic (ROC) curves were used to determine dichotomous classification parameters. Multi-category ROC surfaces were evaluated to classify the three stages of cognitive dysfunction. Results Dichotomous classification using the ROC curve analyses showed that the area under the curve was 0.92 for dementia for subjects without dementia and 0.96 for dementia in controls. Simultaneous multi-category classification analyses showed that the volume under the ROC surface (VUS) was 0.57 and that the derived optimal cut-off points were 2 and 8 for controls, MCI, and dementia. The estimated Youden index for the KDSQ was 0.48, and the derived optimal cut-off points were 5 and 10. The overall classification accuracy of the VUS and Youden index was 61.2% and 58.6%, respectively. Conclusion The KDSQ is useful for classifying dichotomous and multi-category stages of cognitive dysfunction.

Original languageEnglish
Pages (from-to)384-389
Number of pages6
JournalPsychiatry Investigation
Volume15
Issue number4
DOIs
Publication statusPublished - 2018 Apr 1

Fingerprint

Cognition
Dementia
ROC Curve
Aptitude
Cognitive Dysfunction
Surveys and Questionnaires
Area Under Curve

Keywords

  • Classifying
  • Dement
  • KDSQ
  • Mild cognitive impairment
  • Screening

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Screening for normal cognition, mild cognitive impairment, and dementia with the Korean dementia screening questionnaire. / Lee, Sun Ju; Han, Jung Hoon; Hwang, Jung Won; Paik, Jong Woo; Han, Changsu; Park, Moon Ho.

In: Psychiatry Investigation, Vol. 15, No. 4, 01.04.2018, p. 384-389.

Research output: Contribution to journalArticle

@article{dcfac5c059ca4c52888596595c4327d0,
title = "Screening for normal cognition, mild cognitive impairment, and dementia with the Korean dementia screening questionnaire",
abstract = "Objective The Korean Dementia Screening Questionnaire (KDSQ) is an informant-based instrument used to screen for cognitive dysfunction. However, its ability to only dichotomously discriminate between dementia and normal cognition has been previously investigated. This study investigated the ability of the KDSQ to classify not only dichotomous but also multiple stages of cognitive dysfunction. Methods We examined 582 participants. Receiver operating characteristic (ROC) curves were used to determine dichotomous classification parameters. Multi-category ROC surfaces were evaluated to classify the three stages of cognitive dysfunction. Results Dichotomous classification using the ROC curve analyses showed that the area under the curve was 0.92 for dementia for subjects without dementia and 0.96 for dementia in controls. Simultaneous multi-category classification analyses showed that the volume under the ROC surface (VUS) was 0.57 and that the derived optimal cut-off points were 2 and 8 for controls, MCI, and dementia. The estimated Youden index for the KDSQ was 0.48, and the derived optimal cut-off points were 5 and 10. The overall classification accuracy of the VUS and Youden index was 61.2{\%} and 58.6{\%}, respectively. Conclusion The KDSQ is useful for classifying dichotomous and multi-category stages of cognitive dysfunction.",
keywords = "Classifying, Dement, KDSQ, Mild cognitive impairment, Screening",
author = "Lee, {Sun Ju} and Han, {Jung Hoon} and Hwang, {Jung Won} and Paik, {Jong Woo} and Changsu Han and Park, {Moon Ho}",
year = "2018",
month = "4",
day = "1",
doi = "10.30773/pi.2017.08.24",
language = "English",
volume = "15",
pages = "384--389",
journal = "Psychiatry Investigation",
issn = "1738-3684",
publisher = "Korean Neuropsychiatric Association",
number = "4",

}

TY - JOUR

T1 - Screening for normal cognition, mild cognitive impairment, and dementia with the Korean dementia screening questionnaire

AU - Lee, Sun Ju

AU - Han, Jung Hoon

AU - Hwang, Jung Won

AU - Paik, Jong Woo

AU - Han, Changsu

AU - Park, Moon Ho

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Objective The Korean Dementia Screening Questionnaire (KDSQ) is an informant-based instrument used to screen for cognitive dysfunction. However, its ability to only dichotomously discriminate between dementia and normal cognition has been previously investigated. This study investigated the ability of the KDSQ to classify not only dichotomous but also multiple stages of cognitive dysfunction. Methods We examined 582 participants. Receiver operating characteristic (ROC) curves were used to determine dichotomous classification parameters. Multi-category ROC surfaces were evaluated to classify the three stages of cognitive dysfunction. Results Dichotomous classification using the ROC curve analyses showed that the area under the curve was 0.92 for dementia for subjects without dementia and 0.96 for dementia in controls. Simultaneous multi-category classification analyses showed that the volume under the ROC surface (VUS) was 0.57 and that the derived optimal cut-off points were 2 and 8 for controls, MCI, and dementia. The estimated Youden index for the KDSQ was 0.48, and the derived optimal cut-off points were 5 and 10. The overall classification accuracy of the VUS and Youden index was 61.2% and 58.6%, respectively. Conclusion The KDSQ is useful for classifying dichotomous and multi-category stages of cognitive dysfunction.

AB - Objective The Korean Dementia Screening Questionnaire (KDSQ) is an informant-based instrument used to screen for cognitive dysfunction. However, its ability to only dichotomously discriminate between dementia and normal cognition has been previously investigated. This study investigated the ability of the KDSQ to classify not only dichotomous but also multiple stages of cognitive dysfunction. Methods We examined 582 participants. Receiver operating characteristic (ROC) curves were used to determine dichotomous classification parameters. Multi-category ROC surfaces were evaluated to classify the three stages of cognitive dysfunction. Results Dichotomous classification using the ROC curve analyses showed that the area under the curve was 0.92 for dementia for subjects without dementia and 0.96 for dementia in controls. Simultaneous multi-category classification analyses showed that the volume under the ROC surface (VUS) was 0.57 and that the derived optimal cut-off points were 2 and 8 for controls, MCI, and dementia. The estimated Youden index for the KDSQ was 0.48, and the derived optimal cut-off points were 5 and 10. The overall classification accuracy of the VUS and Youden index was 61.2% and 58.6%, respectively. Conclusion The KDSQ is useful for classifying dichotomous and multi-category stages of cognitive dysfunction.

KW - Classifying

KW - Dement

KW - KDSQ

KW - Mild cognitive impairment

KW - Screening

UR - http://www.scopus.com/inward/record.url?scp=85053633798&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053633798&partnerID=8YFLogxK

U2 - 10.30773/pi.2017.08.24

DO - 10.30773/pi.2017.08.24

M3 - Article

VL - 15

SP - 384

EP - 389

JO - Psychiatry Investigation

JF - Psychiatry Investigation

SN - 1738-3684

IS - 4

ER -