See-through technology for biological tissue: 3-dimensional visualization of macromolecules

Eunsoo Lee, Hyun Jung Kim, Woong Sun

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

Tissue clearing technology is currently one of the fastest growing fields in biomedical sciences. Tissue clearing techniques have become a powerful approach to understand further the structural information of intact biological tissues. Moreover, technological improvements in tissue clearing and optics allowed the visualization of neural network in the whole brain tissue with subcellular resolution. Here, we described an overview of various tissue-clearing techniques, with focus on the tissue-hydrogel mediated clearing methods, and discussed the main advantages and limitations of transparent tissue for clinical diagnosis.

Original languageEnglish
Pages (from-to)S15-S22
JournalInternational Neurourology Journal
Volume20
DOIs
Publication statusPublished - 2016 May 1

Keywords

  • Imaging
  • Immunolabeling
  • Molecular diagnosis
  • Neuroscience
  • Optical tissue clearing
  • Three-dimensional

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Urology

Fingerprint Dive into the research topics of 'See-through technology for biological tissue: 3-dimensional visualization of macromolecules'. Together they form a unique fingerprint.

  • Cite this