Selective and sensitive detection of metal ions by plasmonic resonance energy transfer-based nanospectroscopy

Yeonho Choi, Younggeun Park, Taewook Kang, Luke P. Lee

Research output: Contribution to journalArticle

167 Citations (Scopus)

Abstract

Highly selective and sensitive optical methods for the detection of metal ions have had a substantial impact on molecular biology1-3, environmental monitoring4-10 and other areas of research. Here we demonstrate a new method for detecting metal ions that is based on selective plasmonic resonance energy transfer (PRET) between conjugated metal-ligand complexes and a single gold nanoplasmonic probe. In addition to offering high spatial resolution due to the small size of the probe, our method is 100 to 1,000 times more sensitive than organic reporter-based methods3-8. Moreover, it can achieve high selectivity owing to the selective formation of Cu2+ complexes and selective resonant quenching of the gold nanoplasmonic probe by the conjugated complexes. We expect that PRET-based metal ion sensing could have applications in cellular imaging, systems biology and environmental monitoring.

Original languageEnglish
Pages (from-to)742-746
Number of pages5
JournalNature Nanotechnology
Volume4
Issue number11
DOIs
Publication statusPublished - 2009 Nov 1
Externally publishedYes

Fingerprint

Energy Transfer
Energy transfer
Metal ions
metal ions
Metals
energy transfer
Ions
Gold
gold
environmental monitoring
Systems Biology
probes
Environmental Monitoring
Coordination Complexes
biology
Imaging systems
Quenching
spatial resolution
selectivity
quenching

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Materials Science(all)
  • Electrical and Electronic Engineering
  • Condensed Matter Physics
  • Atomic and Molecular Physics, and Optics

Cite this

Selective and sensitive detection of metal ions by plasmonic resonance energy transfer-based nanospectroscopy. / Choi, Yeonho; Park, Younggeun; Kang, Taewook; Lee, Luke P.

In: Nature Nanotechnology, Vol. 4, No. 11, 01.11.2009, p. 742-746.

Research output: Contribution to journalArticle

Choi, Yeonho ; Park, Younggeun ; Kang, Taewook ; Lee, Luke P. / Selective and sensitive detection of metal ions by plasmonic resonance energy transfer-based nanospectroscopy. In: Nature Nanotechnology. 2009 ; Vol. 4, No. 11. pp. 742-746.
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