Self-assembly of gold nanoparticles in a block copolymer aggregate template driven by hydrophobic interactions

Jong Dae Jang, Sang Woo Jeon, Young Jin Yoon, Joona Bang, Young Soo Han, Tae Hwan Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We have investigated various self-assembled structures of gold nanoparticle (AuNP)-block copolymer complexes in aqueous solution. Depending on the micellar phase of the two kinds of block copolymer mixtures, the AuNPs were successfully entrapped in the hydrophobic region of the block copolymer micelles, and this is driven by hydrophobic interactions. Small angle neutron scattering (SANS) measurements revealed that the AuNP-polymer complex formed various nanostructures, such as spherical, cylindrical and vesicular structures, and that the AuNPs were localized in the hydrophobic region (which is the core part and the inner layer for the spherical and cylindrical micelles and vesicles, respectively) of the micelles, and this is consistent with the results of TEM measurements. In particular, for the vesicular structures, the AuNPs were localized in the hydrophobic region as a form of the single layered structure. This study provides an easy and novel method to entrap the AuNP complex and control its localized structure in soft materials without complicated procedures. In addition, AuNPs entrapped in the unilamellar polymeric vesicles can be utilized as imageable drug carriers, carriers for catalysts, drug or enzyme deliverers and as nanoreactors or nanocarriers.

Original languageEnglish
Pages (from-to)6269-6277
Number of pages9
JournalPolymer Chemistry
Volume10
Issue number46
DOIs
Publication statusPublished - 2019 Dec 14

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

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