Self-deprotonation and colorization of 1,3-bis(dicyanomethylidene)indan in polar media: A facile route to a minimal polymethine dye for NIR fluorescence imaging

Jeongyun Heo, Chang Keun Lim, Dong Ryeol Whang, Jiyoung Shin, Seo Young Jeong, Soo Young Park, Ick Chan Kwon, Sehoon Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Colorless 1,3-bis(dicyanomethylidene)indan is an organic acid (pK a≈3.0) that turns blue in polar media owing to self-deprotonation. Moreover, its colored conjugate base shows potential as a minimal anionic polymethine dye for probing biomolecules in cells and in vivo through noncovalent complexation and near-infrared fluorescence signaling.

Original languageEnglish
Pages (from-to)8699-8704
Number of pages6
JournalChemistry - A European Journal
Volume18
Issue number28
DOIs
Publication statusPublished - 2012 Jul 9
Externally publishedYes

Keywords

  • fluorescence
  • fluorescent probes
  • imaging agents
  • near-infrared spectroscopy
  • polymethines

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Self-deprotonation and colorization of 1,3-bis(dicyanomethylidene)indan in polar media: A facile route to a minimal polymethine dye for NIR fluorescence imaging'. Together they form a unique fingerprint.

  • Cite this