Sensitive optical bio-sensing of p-type WSe2 hybridized with fluorescent dye attached DNA by doping and de-doping effects

Kyu Hyun Han, Jun Young Kim, Seong Gi Jo, Changwon Seo, Jeongyong Kim, Jinsoo Joo

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Layered transition metal dichalcogenides, such as MoS2, WSe2 and WS2, are exciting two-dimensional (2D) materials because they possess tunable optical and electrical properties that depend on the number of layers. In this study, the nanoscale photoluminescence (PL) characteristics of the p-type WSe2 monolayer, and WSe2 layers hybridized with the fluorescent dye Cy3 attached to probe-DNA (Cy3/p-DNA), have been investigated as a function of the concentration of Cy3/DNA by using high-resolution laser confocal microscopy. With increasing concentration of Cy3/p-DNA, the measured PL intensity decreases and its peak is red-shifted, suggesting that the WSe2 layer has been p-type doped with Cy3/p-DNA. Then, the PL intensity of the WSe2/Cy3/p-DNA hybrid system increases and the peak is blue-shifted through hybridization with relatively small amounts of target-DNA (t-DNA) (50-100 nM). This effect originates from charge and energy transfer from the Cy3/DNA to the WSe2. For t-DNA detection, our systems using p-type WSe2 have the merit in terms of the increase of PL intensity. The p-type WSe2 monolayers can be a promising nanoscale 2D material for sensitive optical bio-sensing based on the doping and de-doping responses to biomaterials.

Original languageEnglish
Article number435501
JournalNanotechnology
Volume28
Issue number43
DOIs
Publication statusPublished - 2017 Sep 26

Fingerprint

Fluorescent Dyes
DNA Probes
DNA
Dyes
Doping (additives)
Photoluminescence
Confocal Microscopy
Monolayers
Confocal microscopy
Energy Transfer
Biocompatible Materials
Hybrid systems
Energy transfer
Transition metals
Charge transfer
Electric properties
Optical properties
Metals
Lasers
Biomaterials

Keywords

  • bio-sensing
  • doping
  • photoluminescence
  • transition metal dichalcogenide
  • WSe

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Sensitive optical bio-sensing of p-type WSe2 hybridized with fluorescent dye attached DNA by doping and de-doping effects. / Han, Kyu Hyun; Kim, Jun Young; Jo, Seong Gi; Seo, Changwon; Kim, Jeongyong; Joo, Jinsoo.

In: Nanotechnology, Vol. 28, No. 43, 435501, 26.09.2017.

Research output: Contribution to journalArticle

Han, Kyu Hyun ; Kim, Jun Young ; Jo, Seong Gi ; Seo, Changwon ; Kim, Jeongyong ; Joo, Jinsoo. / Sensitive optical bio-sensing of p-type WSe2 hybridized with fluorescent dye attached DNA by doping and de-doping effects. In: Nanotechnology. 2017 ; Vol. 28, No. 43.
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