Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea

Jin Ho Kim, Hak Yang Kim, Na Young Kim, Sang Woo Kim, Jae Gyu Kim, Jae Jun Kim, Im Hwan Roe, Jeong Kee Seo, Jae Geon Sim, Hyoengsik Ahn, Byung Chul Yoon, Sang Woo Lee, Yong Chan Lee, In Sik Chung, Hwoon Yong Jung, Weon Seon Hong, Kyoo Wan Choi

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

Background: Helicobacter pylori infection occurs throughout the world and causes gastroduodenal diseases in all age groups. The prevalence of H. pylori infection varies between countries and races. The aim of this study was to evaluate the seroprevalence of H. pylori infection in asymptomatic healthy people in South Korea. Methods: From March 1998 to October 1998, 5732 asymptomatic subjects who responded to the self-assessment questionnaires from 54 hospitals in South Korea were enrolled in this study. The serum levels of antibodies for H. pylori immunoglobulinG were measured by using an ELISA test. Results: The overall seroprevalence of H. pylori infection was 46.6% and there was no statistical difference between males (47.2%) and females (45.9%). In adults, a significant difference was observed between genders. According to the geographic areas, the high prevalent provinces were Kangwon (53.4%), Cheju (52.9%) and Cholla province (50.6%); Seoul (41.9%) was the lowest prevalent area. The seroprevalence increased with age and was highest when patients were aged in their 40s (78.5%). The characteristic feature of our study was that the infection rate was steeply increased in three age groups (10-12 year olds, 16-19 year olds and those aged in their 20s). In Seoul, there was no difference in the prevalence rate among the districts studied. Conclusions: This nation-wide seroprevalence of H. pylori infection in South Korea was 46.6%, which showed the transition from a developing country to a developed country. More studies on the epidemiological factors and the route of transmission of H. pylori infection should be warranted.

Original languageEnglish
Pages (from-to)969-975
Number of pages7
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume16
Issue number9
DOIs
Publication statusPublished - 2001 Jan 1
Externally publishedYes

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Republic of Korea
Seroepidemiologic Studies
Helicobacter Infections
Helicobacter pylori
Age Groups
Developed Countries
Developing Countries
Epidemiologic Studies
Enzyme-Linked Immunosorbent Assay
Antibodies
Infection
Serum

Keywords

  • Helicobacter pylori
  • Seroprevalence
  • South Korea

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea. / Kim, Jin Ho; Kim, Hak Yang; Kim, Na Young; Kim, Sang Woo; Kim, Jae Gyu; Kim, Jae Jun; Roe, Im Hwan; Seo, Jeong Kee; Sim, Jae Geon; Ahn, Hyoengsik; Yoon, Byung Chul; Lee, Sang Woo; Lee, Yong Chan; Chung, In Sik; Jung, Hwoon Yong; Hong, Weon Seon; Choi, Kyoo Wan.

In: Journal of Gastroenterology and Hepatology (Australia), Vol. 16, No. 9, 01.01.2001, p. 969-975.

Research output: Contribution to journalArticle

Kim, JH, Kim, HY, Kim, NY, Kim, SW, Kim, JG, Kim, JJ, Roe, IH, Seo, JK, Sim, JG, Ahn, H, Yoon, BC, Lee, SW, Lee, YC, Chung, IS, Jung, HY, Hong, WS & Choi, KW 2001, 'Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea', Journal of Gastroenterology and Hepatology (Australia), vol. 16, no. 9, pp. 969-975. https://doi.org/10.1046/j.1440-1746.2001.02568.x
Kim, Jin Ho ; Kim, Hak Yang ; Kim, Na Young ; Kim, Sang Woo ; Kim, Jae Gyu ; Kim, Jae Jun ; Roe, Im Hwan ; Seo, Jeong Kee ; Sim, Jae Geon ; Ahn, Hyoengsik ; Yoon, Byung Chul ; Lee, Sang Woo ; Lee, Yong Chan ; Chung, In Sik ; Jung, Hwoon Yong ; Hong, Weon Seon ; Choi, Kyoo Wan. / Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea. In: Journal of Gastroenterology and Hepatology (Australia). 2001 ; Vol. 16, No. 9. pp. 969-975.
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abstract = "Background: Helicobacter pylori infection occurs throughout the world and causes gastroduodenal diseases in all age groups. The prevalence of H. pylori infection varies between countries and races. The aim of this study was to evaluate the seroprevalence of H. pylori infection in asymptomatic healthy people in South Korea. Methods: From March 1998 to October 1998, 5732 asymptomatic subjects who responded to the self-assessment questionnaires from 54 hospitals in South Korea were enrolled in this study. The serum levels of antibodies for H. pylori immunoglobulinG were measured by using an ELISA test. Results: The overall seroprevalence of H. pylori infection was 46.6{\%} and there was no statistical difference between males (47.2{\%}) and females (45.9{\%}). In adults, a significant difference was observed between genders. According to the geographic areas, the high prevalent provinces were Kangwon (53.4{\%}), Cheju (52.9{\%}) and Cholla province (50.6{\%}); Seoul (41.9{\%}) was the lowest prevalent area. The seroprevalence increased with age and was highest when patients were aged in their 40s (78.5{\%}). The characteristic feature of our study was that the infection rate was steeply increased in three age groups (10-12 year olds, 16-19 year olds and those aged in their 20s). In Seoul, there was no difference in the prevalence rate among the districts studied. Conclusions: This nation-wide seroprevalence of H. pylori infection in South Korea was 46.6{\%}, which showed the transition from a developing country to a developed country. More studies on the epidemiological factors and the route of transmission of H. pylori infection should be warranted.",
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AU - Kim, Jin Ho

AU - Kim, Hak Yang

AU - Kim, Na Young

AU - Kim, Sang Woo

AU - Kim, Jae Gyu

AU - Kim, Jae Jun

AU - Roe, Im Hwan

AU - Seo, Jeong Kee

AU - Sim, Jae Geon

AU - Ahn, Hyoengsik

AU - Yoon, Byung Chul

AU - Lee, Sang Woo

AU - Lee, Yong Chan

AU - Chung, In Sik

AU - Jung, Hwoon Yong

AU - Hong, Weon Seon

AU - Choi, Kyoo Wan

PY - 2001/1/1

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N2 - Background: Helicobacter pylori infection occurs throughout the world and causes gastroduodenal diseases in all age groups. The prevalence of H. pylori infection varies between countries and races. The aim of this study was to evaluate the seroprevalence of H. pylori infection in asymptomatic healthy people in South Korea. Methods: From March 1998 to October 1998, 5732 asymptomatic subjects who responded to the self-assessment questionnaires from 54 hospitals in South Korea were enrolled in this study. The serum levels of antibodies for H. pylori immunoglobulinG were measured by using an ELISA test. Results: The overall seroprevalence of H. pylori infection was 46.6% and there was no statistical difference between males (47.2%) and females (45.9%). In adults, a significant difference was observed between genders. According to the geographic areas, the high prevalent provinces were Kangwon (53.4%), Cheju (52.9%) and Cholla province (50.6%); Seoul (41.9%) was the lowest prevalent area. The seroprevalence increased with age and was highest when patients were aged in their 40s (78.5%). The characteristic feature of our study was that the infection rate was steeply increased in three age groups (10-12 year olds, 16-19 year olds and those aged in their 20s). In Seoul, there was no difference in the prevalence rate among the districts studied. Conclusions: This nation-wide seroprevalence of H. pylori infection in South Korea was 46.6%, which showed the transition from a developing country to a developed country. More studies on the epidemiological factors and the route of transmission of H. pylori infection should be warranted.

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