Seroepizootiology of hantavirus infection in indigenous rodents in Korea, during 1995-2000

A. Baek, Luck Ju, Jin Won Song, Kwang Sook Park, Eun Young Kho, Sung Ho Ryu, Richard Yanagihara, Ki-Joon Song

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To better understand the reservoir host range and distribution of hantaviruses in small mammal populations in Korea, a serological survey was conducted on 1,375 wild rodents and 62 insectivores captured in seven provinces during the six-year period, 1995 to 2000. As determined by the indirect immunofluorescent antibody (IFA) test, 90 (13.1%) of 685 Apodemus agrarius, 47 (13.6%) of 345 Apodemus peninsulae, and 4 (6.5%) of 62 Crocidura laciura were seropositive against the Hantaan virus, while 38 (13.5%) of 282 Eothenomys regulus were seropositive against the Puumala virus. Serological evidence for hantavirus infection was not found in 50 Microtus fortis, six Micromys minutus, six Mus musculus, and one Cricetulus triton. Our serological data indicate that hemorrhagic fever with renal syndrome (HFRS)-related hantaviruses are widely distributed in indigenous rodents in Korea. Particularly noteworthy was the high seropositivity rates among Apodemus peninsulae and Eothenomys regulus captured in certain mountainous regions, suggesting that HFRS may be under-reported among nearby residents or among individuals who might visit such areas for recreational or occupational purposes.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalJournal of Microbiology and Biotechnology
Volume12
Issue number1
Publication statusPublished - 2002 Jan 1

Fingerprint

Hantavirus Infections
Murinae
Korea
Viruses
Hantavirus
Hemorrhagic Fever with Renal Syndrome
Rodentia
Mammals
Puumala virus
Hantaan virus
Antibodies
Arvicolinae
Host Specificity
Cricetulus
Population

Keywords

  • Hantavirus
  • Hemorrhagic fever with renal syndrome
  • Rodents

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology
  • Microbiology

Cite this

Seroepizootiology of hantavirus infection in indigenous rodents in Korea, during 1995-2000. / Baek, A.; Ju, Luck; Song, Jin Won; Park, Kwang Sook; Kho, Eun Young; Ryu, Sung Ho; Yanagihara, Richard; Song, Ki-Joon.

In: Journal of Microbiology and Biotechnology, Vol. 12, No. 1, 01.01.2002, p. 53-58.

Research output: Contribution to journalArticle

Baek, A. ; Ju, Luck ; Song, Jin Won ; Park, Kwang Sook ; Kho, Eun Young ; Ryu, Sung Ho ; Yanagihara, Richard ; Song, Ki-Joon. / Seroepizootiology of hantavirus infection in indigenous rodents in Korea, during 1995-2000. In: Journal of Microbiology and Biotechnology. 2002 ; Vol. 12, No. 1. pp. 53-58.
@article{47ac71367ab84955bfdf7c87caebe6f6,
title = "Seroepizootiology of hantavirus infection in indigenous rodents in Korea, during 1995-2000",
abstract = "To better understand the reservoir host range and distribution of hantaviruses in small mammal populations in Korea, a serological survey was conducted on 1,375 wild rodents and 62 insectivores captured in seven provinces during the six-year period, 1995 to 2000. As determined by the indirect immunofluorescent antibody (IFA) test, 90 (13.1{\%}) of 685 Apodemus agrarius, 47 (13.6{\%}) of 345 Apodemus peninsulae, and 4 (6.5{\%}) of 62 Crocidura laciura were seropositive against the Hantaan virus, while 38 (13.5{\%}) of 282 Eothenomys regulus were seropositive against the Puumala virus. Serological evidence for hantavirus infection was not found in 50 Microtus fortis, six Micromys minutus, six Mus musculus, and one Cricetulus triton. Our serological data indicate that hemorrhagic fever with renal syndrome (HFRS)-related hantaviruses are widely distributed in indigenous rodents in Korea. Particularly noteworthy was the high seropositivity rates among Apodemus peninsulae and Eothenomys regulus captured in certain mountainous regions, suggesting that HFRS may be under-reported among nearby residents or among individuals who might visit such areas for recreational or occupational purposes.",
keywords = "Hantavirus, Hemorrhagic fever with renal syndrome, Rodents",
author = "A. Baek and Luck Ju and Song, {Jin Won} and Park, {Kwang Sook} and Kho, {Eun Young} and Ryu, {Sung Ho} and Richard Yanagihara and Ki-Joon Song",
year = "2002",
month = "1",
day = "1",
language = "English",
volume = "12",
pages = "53--58",
journal = "Journal of Microbiology and Biotechnology",
issn = "1017-7825",
publisher = "Korean Society for Microbiolog and Biotechnology",
number = "1",

}

TY - JOUR

T1 - Seroepizootiology of hantavirus infection in indigenous rodents in Korea, during 1995-2000

AU - Baek, A.

AU - Ju, Luck

AU - Song, Jin Won

AU - Park, Kwang Sook

AU - Kho, Eun Young

AU - Ryu, Sung Ho

AU - Yanagihara, Richard

AU - Song, Ki-Joon

PY - 2002/1/1

Y1 - 2002/1/1

N2 - To better understand the reservoir host range and distribution of hantaviruses in small mammal populations in Korea, a serological survey was conducted on 1,375 wild rodents and 62 insectivores captured in seven provinces during the six-year period, 1995 to 2000. As determined by the indirect immunofluorescent antibody (IFA) test, 90 (13.1%) of 685 Apodemus agrarius, 47 (13.6%) of 345 Apodemus peninsulae, and 4 (6.5%) of 62 Crocidura laciura were seropositive against the Hantaan virus, while 38 (13.5%) of 282 Eothenomys regulus were seropositive against the Puumala virus. Serological evidence for hantavirus infection was not found in 50 Microtus fortis, six Micromys minutus, six Mus musculus, and one Cricetulus triton. Our serological data indicate that hemorrhagic fever with renal syndrome (HFRS)-related hantaviruses are widely distributed in indigenous rodents in Korea. Particularly noteworthy was the high seropositivity rates among Apodemus peninsulae and Eothenomys regulus captured in certain mountainous regions, suggesting that HFRS may be under-reported among nearby residents or among individuals who might visit such areas for recreational or occupational purposes.

AB - To better understand the reservoir host range and distribution of hantaviruses in small mammal populations in Korea, a serological survey was conducted on 1,375 wild rodents and 62 insectivores captured in seven provinces during the six-year period, 1995 to 2000. As determined by the indirect immunofluorescent antibody (IFA) test, 90 (13.1%) of 685 Apodemus agrarius, 47 (13.6%) of 345 Apodemus peninsulae, and 4 (6.5%) of 62 Crocidura laciura were seropositive against the Hantaan virus, while 38 (13.5%) of 282 Eothenomys regulus were seropositive against the Puumala virus. Serological evidence for hantavirus infection was not found in 50 Microtus fortis, six Micromys minutus, six Mus musculus, and one Cricetulus triton. Our serological data indicate that hemorrhagic fever with renal syndrome (HFRS)-related hantaviruses are widely distributed in indigenous rodents in Korea. Particularly noteworthy was the high seropositivity rates among Apodemus peninsulae and Eothenomys regulus captured in certain mountainous regions, suggesting that HFRS may be under-reported among nearby residents or among individuals who might visit such areas for recreational or occupational purposes.

KW - Hantavirus

KW - Hemorrhagic fever with renal syndrome

KW - Rodents

UR - http://www.scopus.com/inward/record.url?scp=0036209132&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036209132&partnerID=8YFLogxK

M3 - Article

VL - 12

SP - 53

EP - 58

JO - Journal of Microbiology and Biotechnology

JF - Journal of Microbiology and Biotechnology

SN - 1017-7825

IS - 1

ER -