Serum calcium level is associated with metabolic syndrome in elderly women

Geum Joon Cho, Jung Ho Shin, Kyong Wook Yi, Hyun Tae Park, Tak Kim, Jun Young Hur, Sun Haeng Kim

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)

    Abstract

    Objective: To investigate the association between serum calcium level and metabolic syndrome, defined using the National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III) definition, in Korean elderly women. Study design: We conducted a cross-sectional study of 1941 elderly women (mean age: 65.16 ± 4.58 years) who participated in annual health examinations at Korea university Medical Center between January 1, 2006 and December 31, 2009 and had normal serum calcium levels. Results: Women with metabolic syndrome had higher serum calcium levels than those without metabolic syndrome (9.26 ± 0.35 vs. 9.20 ± 0.33, P < 0.001). In multiple logistic regression analysis, serum calcium level within normal range was positively associated with the risk of having metabolic syndrome (odds ratio 2.12, 95% confidence interval 1.50-2.98). With regard to components of metabolic syndrome, serum calcium level was also positively associated with the risk of having high triglyceride, and high glucose, whereas it was inversely associated with the risk of having low high density lipoprotein. However, there was no association of serum calcium level with abdominal obesity or high blood pressure. Conclusions: The higher was the level of calcium within normal range, the greater were the odds of metabolic syndrome in healthy and elderly women. Prospective studies are needed to investigate the role of calcium in the development of metabolic syndrome in the future.

    Original languageEnglish
    Pages (from-to)382-386
    Number of pages5
    JournalMaturitas
    Volume68
    Issue number4
    DOIs
    Publication statusPublished - 2011 Apr

    Keywords

    • Calcium
    • Elderly
    • Metabolic syndrome

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Obstetrics and Gynaecology

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