Serum ferritin in healthy subjects and type 2 diabetic patients.

Nan Hee Kim, J. H. Oh, Kyung Mook Choi, Y. H. Kim, Sei-Hyun Baik, D. S. Choi, S. J. Kim

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Abstract

In order to study the relationship between the serum ferritin level and the components of the insulin resistance syndrome in type 2 diabetic patients, we evaluated fifty type 2 diabetic patients who were selected according to NDDG/WHO criteria from those patients attending Korea University Hospital from 1997 to 1998. Twenty-five healthy non-diabetic subjects of comparable age and sex distribution acted as a control group. The results showed that the value of log ferritin was higher in the type 2 diabetes patients than the control subjects, but not at a statistically significant level (p = 0.09). Log ferritin was correlated with fasting blood sugar level (r = 0.235, p = 0.048) and body mass index (BMI) (r = 0.285, p = 0.05). In the type 2 diabetic patients, log ferritin was correlated with fasting C-peptide (r = 0.478, p = 0.009). In the control subjects, log ferritin was correlated only with BMI (r = 0.477, p = 0.012). In a stepwise multiple regression analysis, the diabetic group showed a significant correlation between fasting C-peptide and log ferritin (p = 0.001). In the control group, the fasting sugar level was significantly correlated with log ferritin (p = 0.034). These results suggest that serum ferritin can be employed as a marker of not only glucose homeostasis but also insulin resistance both in type 2 diabetic and control subjects.

Original languageEnglish
Pages (from-to)387-392
Number of pages6
JournalYonsei Medical Journal
Volume41
Issue number3
Publication statusPublished - 2000 Jun 1

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Ferritins
Healthy Volunteers
Serum
Fasting
C-Peptide
Insulin Resistance
Body Mass Index
Control Groups
Sex Distribution
Age Distribution
Korea
Type 2 Diabetes Mellitus
Blood Glucose
Homeostasis
Regression Analysis
Glucose

ASJC Scopus subject areas

  • Medicine(all)

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Serum ferritin in healthy subjects and type 2 diabetic patients. / Kim, Nan Hee; Oh, J. H.; Choi, Kyung Mook; Kim, Y. H.; Baik, Sei-Hyun; Choi, D. S.; Kim, S. J.

In: Yonsei Medical Journal, Vol. 41, No. 3, 01.06.2000, p. 387-392.

Research output: Contribution to journalArticle

Kim, NH, Oh, JH, Choi, KM, Kim, YH, Baik, S-H, Choi, DS & Kim, SJ 2000, 'Serum ferritin in healthy subjects and type 2 diabetic patients.', Yonsei Medical Journal, vol. 41, no. 3, pp. 387-392.
Kim, Nan Hee ; Oh, J. H. ; Choi, Kyung Mook ; Kim, Y. H. ; Baik, Sei-Hyun ; Choi, D. S. ; Kim, S. J. / Serum ferritin in healthy subjects and type 2 diabetic patients. In: Yonsei Medical Journal. 2000 ; Vol. 41, No. 3. pp. 387-392.
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