Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans-A descriptive epidemiologic study

Akira Sekikawa, Laufey Steingrimsdottir, Hirotsugu Ueshima, Chol Shin, J. David Curb, Rhobert W. Evans, Alda M. Hauksdottir, Aya Kadota, Jina Choo, Kamal Masaki, Bolli Thorsson, Lenore J. Launer, Melisa E. Garcia, Hiroshi Maegawa, Bradley J. Willcox, Gudny Eiriksdottir, Akira Fujiyoshi, Katsuyuki Miura, Tamara B. Harris, Lewis H. KullerVilmundur Gudnason

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

In the 1990s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally, a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US.

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalProstaglandins Leukotrienes and Essential Fatty Acids
Volume87
Issue number1
DOIs
Publication statusPublished - 2012 Jul

Keywords

  • Coronary heart disease
  • Descriptive epidemiologic study
  • Docosahexaenoic acid
  • Eicosapentaenoic acid
  • N-3 fatty acids

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology

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