Serum lipid levels and suicide attempts

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Objective: To determine whether a correlation exists between lower serum lipid concentrations and increased suicide risk. Method: Serum lipid profiles were pair-matched for 60 patients who had recently experienced failed attempts at suicide and equal number of non-suicidal psychiatric patients, and normal controls. Suicide attempt severity was scored using Weisman and Worden's risk-rescue rating scale. Results: (a) Total serum cholesterol and low density lipoprotein level were found to be lower in the parasuicidal population at statistically significant levels (P < 0.01 and <0.05, respectively); (b) triglyceride concentrations were lower in suicide attempters with major depression compared with non-suicidal depressed patients; and (c) risk-rescue rating scores were negatively correlated with total serum cholesterol levels (r = -0.347, P = 0.007). Conclusion: Low lipid metabolism may be a potential biological marker in the assessment of suicide risk. Further investigations are necessary to elucidate the biological mechanisms of these findings.

Original languageEnglish
Pages (from-to)215-221
Number of pages7
JournalActa Psychiatrica Scandinavica
Volume108
Issue number3
DOIs
Publication statusPublished - 2003 Sep 1

Keywords

  • Cholesterol
  • Depression
  • Lipid
  • Parasuicide
  • Personality disorder
  • Suicide

ASJC Scopus subject areas

  • Psychiatry and Mental health

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