Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome.

Hae Rim Kim, Young-Sun Lee, Hyung Joon Yim, Hyun Joo Lee, Ja Young Ryu, Hyun Jung Lee, Eileen L. Yoon, Sun Jae Lee, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Rok Sun Choung, Sang Woo Lee, Jai Hyun Choi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a case of severe ischemic bowel necrosis in a 46-year-old cirrhotic patient treated with terlipressin. Although the patient received bowel resection, death occurred due to ongoing hypotension and metabolic acidosis. Attention should be paid to patients complaining of abdominal pain during treatment with terlipressin.

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalClinical and molecular hepatology
Volume19
Issue number4
DOIs
Publication statusPublished - 2013 Jan 1

Fingerprint

Hepatorenal Syndrome
Necrosis
Vasopressins
Viscera
Therapeutics
Acidosis
Hypotension
Abdominal Pain
Ischemia
Myocardial Infarction
Hemorrhage
Skin
terlipressin
Incidence

ASJC Scopus subject areas

  • Medicine(all)
  • Hepatology
  • Molecular Biology

Cite this

Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome. / Kim, Hae Rim; Lee, Young-Sun; Yim, Hyung Joon; Lee, Hyun Joo; Ryu, Ja Young; Lee, Hyun Jung; Yoon, Eileen L.; Lee, Sun Jae; Hyun, Jong Jin; Jung, Sung Woo; Koo, Ja Seol; Choung, Rok Sun; Lee, Sang Woo; Choi, Jai Hyun.

In: Clinical and molecular hepatology, Vol. 19, No. 4, 01.01.2013, p. 417-420.

Research output: Contribution to journalArticle

Kim, Hae Rim ; Lee, Young-Sun ; Yim, Hyung Joon ; Lee, Hyun Joo ; Ryu, Ja Young ; Lee, Hyun Jung ; Yoon, Eileen L. ; Lee, Sun Jae ; Hyun, Jong Jin ; Jung, Sung Woo ; Koo, Ja Seol ; Choung, Rok Sun ; Lee, Sang Woo ; Choi, Jai Hyun. / Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome. In: Clinical and molecular hepatology. 2013 ; Vol. 19, No. 4. pp. 417-420.
@article{2e6ab52ddaf54077813809b2b2bcf29d,
title = "Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome.",
abstract = "Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a case of severe ischemic bowel necrosis in a 46-year-old cirrhotic patient treated with terlipressin. Although the patient received bowel resection, death occurred due to ongoing hypotension and metabolic acidosis. Attention should be paid to patients complaining of abdominal pain during treatment with terlipressin.",
author = "Kim, {Hae Rim} and Young-Sun Lee and Yim, {Hyung Joon} and Lee, {Hyun Joo} and Ryu, {Ja Young} and Lee, {Hyun Jung} and Yoon, {Eileen L.} and Lee, {Sun Jae} and Hyun, {Jong Jin} and Jung, {Sung Woo} and Koo, {Ja Seol} and Choung, {Rok Sun} and Lee, {Sang Woo} and Choi, {Jai Hyun}",
year = "2013",
month = "1",
day = "1",
doi = "10.3350/cmh.2013.19.4.417",
language = "English",
volume = "19",
pages = "417--420",
journal = "Clinical and molecular hepatology",
issn = "2287-2728",
publisher = "Korean Association for the Study of the Liver",
number = "4",

}

TY - JOUR

T1 - Severe ischemic bowel necrosis caused by terlipressin during treatment of hepatorenal syndrome.

AU - Kim, Hae Rim

AU - Lee, Young-Sun

AU - Yim, Hyung Joon

AU - Lee, Hyun Joo

AU - Ryu, Ja Young

AU - Lee, Hyun Jung

AU - Yoon, Eileen L.

AU - Lee, Sun Jae

AU - Hyun, Jong Jin

AU - Jung, Sung Woo

AU - Koo, Ja Seol

AU - Choung, Rok Sun

AU - Lee, Sang Woo

AU - Choi, Jai Hyun

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a case of severe ischemic bowel necrosis in a 46-year-old cirrhotic patient treated with terlipressin. Although the patient received bowel resection, death occurred due to ongoing hypotension and metabolic acidosis. Attention should be paid to patients complaining of abdominal pain during treatment with terlipressin.

AB - Terlipressin is a vasopressin analogue that is widely used in the treatment of hepatorenal syndrome or variceal bleeding. Because it acts mainly on splanchnic vessels, terlipressin has a lower incidence of severe ischemic complications than does vasopressin. However, it can still lead to serious complications such as myocardial infarction, skin necrosis, or bowel ischemia. Herein we report a case of severe ischemic bowel necrosis in a 46-year-old cirrhotic patient treated with terlipressin. Although the patient received bowel resection, death occurred due to ongoing hypotension and metabolic acidosis. Attention should be paid to patients complaining of abdominal pain during treatment with terlipressin.

UR - http://www.scopus.com/inward/record.url?scp=84907187688&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907187688&partnerID=8YFLogxK

U2 - 10.3350/cmh.2013.19.4.417

DO - 10.3350/cmh.2013.19.4.417

M3 - Article

C2 - 24459647

AN - SCOPUS:84907187688

VL - 19

SP - 417

EP - 420

JO - Clinical and molecular hepatology

JF - Clinical and molecular hepatology

SN - 2287-2728

IS - 4

ER -