Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)

Hack Lyoung Kim, Myung A. Kim, Wan Joo Shim, Sohee Oh, Mina Kim, Seong-Mi Park, Yong Hyun Kim, Jin Oh Na, Mi Seung Shin, Hyun Ju Yoon, Gil Ja Shin, Yunkyung Cho, Sung Eun Kim, Kyung Soon Hong, Kyoung Im Cho

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

This study was performed to investigate the association between brachial pulse pressure (PP) and the presence/extent of obstructive coronary artery disease (CAD) in men and women. Study data were obtained from a nation-wide registry composed of 632 patients (173 men and 459 women, 58.1±10.5 years) with suspected CAD who underwent invasive coronary angiography. PP was higher in patients with obstructive CAD (≥50% stenosis) than those without CAD in both sexes (P=.032 in men; P<.001 in women). However, PP increased proportionally with the increasing number of obstructed coronary arteries in women (P<.001) but not in men (P=.070). Multiple logistic-regression analyses demonstrated that higher PP (≥50.5 mm Hg) was an independent factor for determining obstructive CAD even after controlling for potential confounders in women (odds ratio, 2.83; 95% confidence interval, 1.40–5.73; P=.004). These results were consistent in 173 selected women matched with 173 men based on age and CAD severity. In conclusion, the association between brachial PP and obstructive CAD was more pronounced in women than in men. Brachial PP can be a simple and useful indicator of CAD especially in women.

Original languageEnglish
Pages (from-to)38-44
Number of pages7
JournalJournal of Clinical Hypertension
Volume19
Issue number1
DOIs
Publication statusPublished - 2017 Jan 1

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)'. Together they form a unique fingerprint.

  • Cite this

    Kim, H. L., Kim, M. A., Shim, W. J., Oh, S., Kim, M., Park, S-M., Kim, Y. H., Na, J. O., Shin, M. S., Yoon, H. J., Shin, G. J., Cho, Y., Kim, S. E., Hong, K. S., & Cho, K. I. (2017). Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE). Journal of Clinical Hypertension, 19(1), 38-44. https://doi.org/10.1111/jch.12862