Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex

Jeong Eun Hyeon, Dae Hee Kang, Sung Ok Han

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

To construct a self-assembled biosensor with signal amplification, a cellulosome system, comprising type I and type II dockerin–cohesin interactions with different specificities, from the anaerobic Clostridia bacterium was applied. The self-assembled biosensor was highly sensitive and achieved 128.1-fold increase in detection levels compared to the control.

Original languageEnglish
Pages (from-to)4790-4793
Number of pages4
JournalAnalyst
Volume139
Issue number19
DOIs
Publication statusPublished - 2014 Aug 26

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

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