Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex

Jeong Eun Hyeon; Dae Hee Kang; Sung Ok Han

doi:10.1039/c4an00856a

Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex

Jeong Eun Hyeon, Dae Hee Kang, Sung Ok Han

Department of Biotechnology

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

To construct a self-assembled biosensor with signal amplification, a cellulosome system, comprising type I and type II dockerin–cohesin interactions with different specificities, from the anaerobic Clostridia bacterium was applied. The self-assembled biosensor was highly sensitive and achieved 128.1-fold increase in detection levels compared to the control.

Original language	English
Pages (from-to)	4790-4793
Number of pages	4
Journal	Analyst
Volume	139
Issue number	19
DOIs	https://doi.org/10.1039/c4an00856a
Publication status	Published - 2014 Aug 26

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy
Electrochemistry

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10.1039/c4an00856a

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abstract = "To construct a self-assembled biosensor with signal amplification, a cellulosome system, comprising type I and type II dockerin–cohesin interactions with different specificities, from the anaerobic Clostridia bacterium was applied. The self-assembled biosensor was highly sensitive and achieved 128.1-fold increase in detection levels compared to the control.",

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Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex

Abstract

ASJC Scopus subject areas

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