Silk stabilized graphene FET enzymatic glucose biosensor

Xueqiu You, James Jungho Pak

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene transistor as the glucose is oxidized by glucose oxidase that was immobilized in silk fibroin film on the graphene FET. This graphene FET biosensor detected glucose range in 3-10 mM, which covers the reference range for diabetes diagnostics. Because this fibroin-encapsulated graphene FET enzymatic biosensor is biocompatible, flexible, and long-term stable, it holds great promise for portable, wearable, and implantable continuous glucose monitoring applications.

Original languageEnglish
Title of host publication2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Pages2443-2446
Number of pages4
DOIs
Publication statusPublished - 2013 Dec 1
Event2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
Duration: 2013 Jun 162013 Jun 20

Other

Other2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
CountrySpain
CityBarcelona
Period13/6/1613/6/20

Fingerprint

Silk
Field effect transistors
Biosensors
Graphene
Glucose
Enzyme immobilization
Glucose oxidase
Medical problems
Proteins
Molecules
Monitoring
Substrates

Keywords

  • Enzyme stabilization
  • Glucose biosensor
  • Graphene FET biosensor
  • Silk protein

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

You, X., & Pak, J. J. (2013). Silk stabilized graphene FET enzymatic glucose biosensor. In 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 (pp. 2443-2446). [6627300] https://doi.org/10.1109/Transducers.2013.6627300

Silk stabilized graphene FET enzymatic glucose biosensor. / You, Xueqiu; Pak, James Jungho.

2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. p. 2443-2446 6627300.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

You, X & Pak, JJ 2013, Silk stabilized graphene FET enzymatic glucose biosensor. in 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013., 6627300, pp. 2443-2446, 2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013, Barcelona, Spain, 13/6/16. https://doi.org/10.1109/Transducers.2013.6627300
You X, Pak JJ. Silk stabilized graphene FET enzymatic glucose biosensor. In 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. p. 2443-2446. 6627300 https://doi.org/10.1109/Transducers.2013.6627300
You, Xueqiu ; Pak, James Jungho. / Silk stabilized graphene FET enzymatic glucose biosensor. 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013. 2013. pp. 2443-2446
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