Silk stabilized graphene FET enzymatic glucose biosensor

Xueqiu You, James Jungho Pak

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene transistor as the glucose is oxidized by glucose oxidase that was immobilized in silk fibroin film on the graphene FET. This graphene FET biosensor detected glucose range in 3-10 mM, which covers the reference range for diabetes diagnostics. Because this fibroin-encapsulated graphene FET enzymatic biosensor is biocompatible, flexible, and long-term stable, it holds great promise for portable, wearable, and implantable continuous glucose monitoring applications.

Original languageEnglish
Title of host publication2013 Transducers and Eurosensors XXVII
Subtitle of host publicationThe 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Pages2443-2446
Number of pages4
DOIs
Publication statusPublished - 2013
Event2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013 - Barcelona, Spain
Duration: 2013 Jun 162013 Jun 20

Publication series

Name2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013

Other

Other2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
CountrySpain
CityBarcelona
Period13/6/1613/6/20

Keywords

  • Enzyme stabilization
  • Glucose biosensor
  • Graphene FET biosensor
  • Silk protein

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

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