TY - GEN
T1 - Silk stabilized graphene FET enzymatic glucose biosensor
AU - You, Xueqiu
AU - Pak, James Jungho
PY - 2013
Y1 - 2013
N2 - This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene transistor as the glucose is oxidized by glucose oxidase that was immobilized in silk fibroin film on the graphene FET. This graphene FET biosensor detected glucose range in 3-10 mM, which covers the reference range for diabetes diagnostics. Because this fibroin-encapsulated graphene FET enzymatic biosensor is biocompatible, flexible, and long-term stable, it holds great promise for portable, wearable, and implantable continuous glucose monitoring applications.
AB - This paper describes a silk fibroin-encapsulated graphene field effect transistor (FET) enzymatic biosensor that utilizes silk protein as both device substrate and enzyme immobilization material. Glucose molecules are detected by the conductance change and the Dirac point shift of the graphene transistor as the glucose is oxidized by glucose oxidase that was immobilized in silk fibroin film on the graphene FET. This graphene FET biosensor detected glucose range in 3-10 mM, which covers the reference range for diabetes diagnostics. Because this fibroin-encapsulated graphene FET enzymatic biosensor is biocompatible, flexible, and long-term stable, it holds great promise for portable, wearable, and implantable continuous glucose monitoring applications.
KW - Enzyme stabilization
KW - Glucose biosensor
KW - Graphene FET biosensor
KW - Silk protein
UR - http://www.scopus.com/inward/record.url?scp=84891719988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84891719988&partnerID=8YFLogxK
U2 - 10.1109/Transducers.2013.6627300
DO - 10.1109/Transducers.2013.6627300
M3 - Conference contribution
AN - SCOPUS:84891719988
SN - 9781467359818
T3 - 2013 Transducers and Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
SP - 2443
EP - 2446
BT - 2013 Transducers and Eurosensors XXVII
T2 - 2013 17th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS and EUROSENSORS 2013
Y2 - 16 June 2013 through 20 June 2013
ER -
