Simultaneous bilateral carotid stenting under the circumstance of neuroprotection device. A retrospective analysis

Young Hen Lee, Taik Kun Kim, Sang-Il Suh, B. J. Kwon, T. H. Lee, O. Ki Kwon, M. H. Han, Nam-Joon Lee, Jong Hyun Kim, H. Y. Seol

Research output: Contribution to journalArticle

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Abstract

In this study, in order to evaluate the feasibility and outcomes of simultaneous bilateral carotid artery stenting (CAS) with the use of neuroprotection in symptomatic patients, we conducted a retrospective analysis of 27 patients (19 men, eight women; median age, 69.2 years), all of whom had been scheduled to undergo bilateral CAS in a single setting. All patients presented with severe atherosclerotic bilateral carotid stenosis (>50% for symptomatic side, >80% for asymptomatic side), exhibiting symptoms of either a cerebrovascular accident or of a transient ischemic attack on at least one side. 48 arteries were treated with self-expandable stents. Neuroprotection devices were utilized for bilateral CAS in 11 patients, and in 16 unilateral CAS patients. We did not perform the second procedure in six patients, in cases in which a patient exhibited (a) hemodynamic instability, (b) a new neurological impairment, or (c) restlessness after a prolonged time for the first CAS. The second procedure was postponed in a staged manner. We achieved a mean residual stenosis of 8.1 ± 5.0 % in the treated lesions. The mean procedural time for bilateral CAS was three hours and 18 minutes. 17 patients (63%) developed transient bradycardia during the balloon dilatation of one or both of the relevant arteries. Three patients (11%) exhibited persistent bradycardia and hypotension, which required the administration of intravenous vasopressors for several days (2-7 days). None of the patients ultimately required pacemakers, or any further therapy. Two of the patients (7%) developed transient ischemic attack during the periprocedural period, but recovered completely. One patient developed a new minor stroke after the first procedure, and the second procedure was delayed in a staged manner. We observed no periprocedural deaths, major strokes, or myocardial infarctions, nor did we detect any cases of hyperperfusion syndrome within 30 days. In summary, simultaneous bilateral CAS with neuroprotection can be performed in a single setting without increased concerns with regard to hyperperfusion syndrome, hemodynamic instability, thrombo-embolism, or procedure time, when the first CAS has been safely completed with no evidence of complications in a well-managed procedure time.

Original languageEnglish
Pages (from-to)141-148
Number of pages8
JournalInterventional Neuroradiology
Volume12
Issue number2
Publication statusPublished - 2006 Jun 1

Fingerprint

Carotid Arteries
Equipment and Supplies
Stroke
Transient Ischemic Attack
Bradycardia
Neuroprotection
Arteries
Hemodynamics
Psychomotor Agitation
Carotid Stenosis
Embolism
Intravenous Administration
Hypotension
Stents
Dilatation
Pathologic Constriction
Myocardial Infarction

Keywords

  • Atherosclerotic carotid stenosis
  • Carotid stenting
  • Neuroprotection devices

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Simultaneous bilateral carotid stenting under the circumstance of neuroprotection device. A retrospective analysis. / Lee, Young Hen; Kim, Taik Kun; Suh, Sang-Il; Kwon, B. J.; Lee, T. H.; Kwon, O. Ki; Han, M. H.; Lee, Nam-Joon; Kim, Jong Hyun; Seol, H. Y.

In: Interventional Neuroradiology, Vol. 12, No. 2, 01.06.2006, p. 141-148.

Research output: Contribution to journalArticle

Lee, Young Hen ; Kim, Taik Kun ; Suh, Sang-Il ; Kwon, B. J. ; Lee, T. H. ; Kwon, O. Ki ; Han, M. H. ; Lee, Nam-Joon ; Kim, Jong Hyun ; Seol, H. Y. / Simultaneous bilateral carotid stenting under the circumstance of neuroprotection device. A retrospective analysis. In: Interventional Neuroradiology. 2006 ; Vol. 12, No. 2. pp. 141-148.
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abstract = "In this study, in order to evaluate the feasibility and outcomes of simultaneous bilateral carotid artery stenting (CAS) with the use of neuroprotection in symptomatic patients, we conducted a retrospective analysis of 27 patients (19 men, eight women; median age, 69.2 years), all of whom had been scheduled to undergo bilateral CAS in a single setting. All patients presented with severe atherosclerotic bilateral carotid stenosis (>50{\%} for symptomatic side, >80{\%} for asymptomatic side), exhibiting symptoms of either a cerebrovascular accident or of a transient ischemic attack on at least one side. 48 arteries were treated with self-expandable stents. Neuroprotection devices were utilized for bilateral CAS in 11 patients, and in 16 unilateral CAS patients. We did not perform the second procedure in six patients, in cases in which a patient exhibited (a) hemodynamic instability, (b) a new neurological impairment, or (c) restlessness after a prolonged time for the first CAS. The second procedure was postponed in a staged manner. We achieved a mean residual stenosis of 8.1 ± 5.0 {\%} in the treated lesions. The mean procedural time for bilateral CAS was three hours and 18 minutes. 17 patients (63{\%}) developed transient bradycardia during the balloon dilatation of one or both of the relevant arteries. Three patients (11{\%}) exhibited persistent bradycardia and hypotension, which required the administration of intravenous vasopressors for several days (2-7 days). None of the patients ultimately required pacemakers, or any further therapy. Two of the patients (7{\%}) developed transient ischemic attack during the periprocedural period, but recovered completely. One patient developed a new minor stroke after the first procedure, and the second procedure was delayed in a staged manner. We observed no periprocedural deaths, major strokes, or myocardial infarctions, nor did we detect any cases of hyperperfusion syndrome within 30 days. In summary, simultaneous bilateral CAS with neuroprotection can be performed in a single setting without increased concerns with regard to hyperperfusion syndrome, hemodynamic instability, thrombo-embolism, or procedure time, when the first CAS has been safely completed with no evidence of complications in a well-managed procedure time.",
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AU - Lee, T. H.

AU - Kwon, O. Ki

AU - Han, M. H.

AU - Lee, Nam-Joon

AU - Kim, Jong Hyun

AU - Seol, H. Y.

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