Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon; Sangyeop Lee; Soo Young Yoon; Soo Ik Chang; Dong Woo Lim; Jaebum Choo

doi:10.1039/c1cc15707h

Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon, Sangyeop Lee, Soo Young Yoon, Soo Ik Chang, Dong Woo Lim, Jaebum Choo

Department of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

113 Citations (Scopus)

Abstract

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

Original language	English
Pages (from-to)	12515-12517
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	46
DOIs	https://doi.org/10.1039/c1cc15707h
Publication status	Published - 2011 Dec 14

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c1cc15707h

Cite this

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abstract = "A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.",

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AU - Chon, Hyangah

AU - Lee, Sangyeop

AU - Yoon, Soo Young

AU - Chang, Soo Ik

AU - Lim, Dong Woo

AU - Choo, Jaebum

PY - 2011/12/14

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AB - A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

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Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Abstract

ASJC Scopus subject areas

UN SDGs

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