Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon, Sangyeop Lee, Soo-Young Yoon, Soo Ik Chang, Dong Woo Lim, Jaebum Choo

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

Original languageEnglish
Pages (from-to)12515-12517
Number of pages3
JournalChemical Communications
Volume47
Issue number46
DOIs
Publication statusPublished - 2011 Dec 14

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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