Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon, Sangyeop Lee, Soo-Young Yoon, Soo Ik Chang, Dong Woo Lim, Jaebum Choo

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

Original languageEnglish
Pages (from-to)12515-12517
Number of pages3
JournalChemical Communications
Volume47
Issue number46
DOIs
Publication statusPublished - 2011 Dec 14

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Nanoprobes
Nanospheres
Immunoassay
Gold
Lung Neoplasms
Blood
Wavelength
Serum
Neoplasms

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

Cite this

Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes. / Chon, Hyangah; Lee, Sangyeop; Yoon, Soo-Young; Chang, Soo Ik; Lim, Dong Woo; Choo, Jaebum.

In: Chemical Communications, Vol. 47, No. 46, 14.12.2011, p. 12515-12517.

Research output: Contribution to journalArticle

Chon, Hyangah ; Lee, Sangyeop ; Yoon, Soo-Young ; Chang, Soo Ik ; Lim, Dong Woo ; Choo, Jaebum. / Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes. In: Chemical Communications. 2011 ; Vol. 47, No. 46. pp. 12515-12517.
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