Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes

Hyangah Chon, Sangyeop Lee, Soo Young Yoon, Soo Ik Chang, Dong Woo Lim, Jaebum Choo

Research output: Contribution to journalArticlepeer-review

100 Citations (Scopus)

Abstract

A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.

Original languageEnglish
Pages (from-to)12515-12517
Number of pages3
JournalChemical Communications
Volume47
Issue number46
DOIs
Publication statusPublished - 2011 Dec 14

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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