Single cardiac cycle three-dimensional intracoronary optical coherence tomography

Tae Shik Kim, Hyun Sang Park, Sun Joo Jang, Joon Woo Song, Han Saem Cho, Sunwon Kim, Brett E. Bouma, Jin Won Kim, Wang Yuhl Oh

    Research output: Contribution to journalArticlepeer-review

    6 Citations (Scopus)

    Abstract

    While high-speed intracoronary optical coherence tomography (OCT) provides three-dimensional (3D) visualization of coronary arteries in vivo, imaging speeds remain insufficient to avoid motion artifacts induced by heartbeat, limiting the clinical utility of OCT. In this paper, we demonstrate development of a high-speed intracoronary OCT system (frame rate: 500 frames/s, pullback speed: 100 mm/s) along with prospective electrocardiogram (ECG) triggering technology, which enabled volumetric imaging of long coronary segments within a single cardiac cycle (70 mm pullback in 0.7 s) with minimal cardiac motion artifact. This technology permitted detailed visualization of 3D architecture of the coronary arterial wall of a swine in vivo and fine structure of the implanted stent.

    Original languageEnglish
    Article number267999
    Pages (from-to)4847-4858
    Number of pages12
    JournalBiomedical Optics Express
    Volume7
    Issue number12
    DOIs
    Publication statusPublished - 2016 Dec 1

    Keywords

    • Endoscopic imaging
    • Medical and biological imaging
    • Optical coherence tomography

    ASJC Scopus subject areas

    • Biotechnology
    • Atomic and Molecular Physics, and Optics

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