Single-session endovascular treatment for symptomatic lower extremity deep vein thrombosis: A feasibility study

Byung Joon Kim, Hwan Hoon Chung, Seung Hwa Lee, Bo-Kyung Je, Young Heon Lee, Bo Kyoung Seo, Baek Hyun Kim, Sang Hoon Cha

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: The risk of complications and discomfort in patients who undergo prolonged infusion of a thrombolytic agent is significant when conventional catheter-directed thrombolysis is used to treat lower extremity deep vein thrombosis (DVT). Purpose: To evaluate the feasibility and safety of single-session endovascular treatment for symptomatic lower extremity DVT. Material and Methods: Single-session endovascular treatment for lower extremity DVT was performed on 29 limbs in 26 patients diagnosed with acute DVT in our institution. Nine patients were male and 17 female, with a mean age of 64 years (range 28-82 years). At 510 min after the locoregional injection of the thrombolytic agent (urokinase) via a 5-Fr catheter to soften the thrombus, aspiration thrombectomy was performed with a large-bore sheath. In patients with an underlying anatomical stenosis or obstruction, combined angioplasty with or without stent placement was performed immediately after the complete removal of the thrombus. We then evaluated the technical and clinical outcomes of the procedure, along with any complications or recurrences of DVT. Results: Technical success was achieved in 24 procedures (82.8%) of single-session endovascular treatment for lower extremity DVT, and clinical success was achieved in 22 (75.9%) of these single-session procedures. Additional catheter-directed thrombolysis procedures were performed on five limbs after repeated aspiration thrombectomies failed to completely remove thrombi in those limbs. Stenotic or occlusive lesions were revealed in 24 limbs and percutaneous angioplasty procedures with or without stent placement were performed in these cases. No major complications resulted from the procedure. Conclusion: Single-session endovascular treatment is a feasible technique that provides acceptable technical and clinical success with excellent safety for treating symptomatic lower extremity DVT.

Original languageEnglish
Pages (from-to)248-255
Number of pages8
JournalActa Radiologica
Volume51
Issue number3
DOIs
Publication statusPublished - 2010 Mar 15

Fingerprint

Feasibility Studies
Venous Thrombosis
Lower Extremity
Extremities
Thrombectomy
Thrombosis
Fibrinolytic Agents
Catheters
Angioplasty
Therapeutics
Stents
Safety
Urokinase-Type Plasminogen Activator
Pathologic Constriction
Recurrence
Injections

Keywords

  • Endovascular treatment
  • Thrombectomy
  • Thrombolysis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

Cite this

Single-session endovascular treatment for symptomatic lower extremity deep vein thrombosis : A feasibility study. / Kim, Byung Joon; Chung, Hwan Hoon; Lee, Seung Hwa; Je, Bo-Kyung; Lee, Young Heon; Seo, Bo Kyoung; Kim, Baek Hyun; Cha, Sang Hoon.

In: Acta Radiologica, Vol. 51, No. 3, 15.03.2010, p. 248-255.

Research output: Contribution to journalArticle

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