Size-selective microvesicle separation microchip based on nanoporous membrane filter

J. H. Park, A. Karimi, Honggu Chun

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Exosomes are smaller than other extracellular vesicles and, therefore require special techniques to separate them from others. To address the issues associated with centrifuge-based isolation of exosomes, namely time consumption and exosome damage, we have developed a separation technique which relies on Brownian motion of these vesicles. Using track-etched nanoporous membrane filter and Brownian motion as the driving force, we have been able to obtain well-isolated exosomes.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages2072-2074
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period15/10/2515/10/29

Keywords

  • Brownian motion
  • Exosome
  • Separation

ASJC Scopus subject areas

  • Control and Systems Engineering

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