Skin absorption potential of ZnO nanoparticles

Sun Yae Kim, Sang Hoon Jeong, Eun Young Lee, Yoon Hee Park, Hyun Cheol Bae, Yeon Sue Jang, Eun Ho Maeng, Meyoung Kon Kim, Sang Wook Son

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.

Original languageEnglish
Pages (from-to)258-261
Number of pages4
JournalToxicology and Environmental Health Sciences
Volume3
Issue number4
DOIs
Publication statusPublished - 2011

Keywords

  • 3D EpiDerm™ model (EPI-200)
  • Absorption
  • Skin
  • ZnO

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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  • Cite this

    Kim, S. Y., Jeong, S. H., Lee, E. Y., Park, Y. H., Bae, H. C., Jang, Y. S., Maeng, E. H., Kim, M. K., & Son, S. W. (2011). Skin absorption potential of ZnO nanoparticles. Toxicology and Environmental Health Sciences, 3(4), 258-261. https://doi.org/10.1007/s13530-011-0100-7