In spite of widely use of zinc oxide (ZnO) nanoparticles (NPs) in cosmetic industry and in our daily lives, there are insufficient data on their potential of skin absorption. This study was conducted to investigate the potential of skin absorption induced by ZnO NPs, especially influences of the surface charge and different particle size. Assessment of potential of skin absorption was estimated using 3D EpiDerm™ model (EPI-200) as human skin equivalent model (HSEM). This study demonstrated no evidence of significant penetration of ZnO NPs into the HSEM after 24 h exposure.
- 3D EpiDerm™ model (EPI-200)
ASJC Scopus subject areas
- Health, Toxicology and Mutagenesis