TY - JOUR
T1 - Soil biota, antimicrobial resistance and planetary health
AU - Zhu, Yong Guan
AU - Zhao, Yi
AU - Zhu, Dong
AU - Gillings, Michael
AU - Penuelas, J.
AU - Ok, Yong Sik
AU - Capon, Anthony
AU - Banwart, S.
N1 - Funding Information:
We thank many people for helping collect samples. This work was funded by the National Natural Science Foundation of China (41571130063), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB15020302 and XDB15020402) and the National Key Research and Development Program of China-International collaborative project from Ministry of Science and Technology (Grant No. 2017YFE0107300). Authors want to specially thank MS Hui-Ling Cui for helping in developing the graphs. Y.G.Z. conceived the manuscript. Y.G.Z. Y.Z. and D.Z. wrote the manuscript. M. G. J. P. Y.S.O. A.C. and S.B. edited the manuscript.
Funding Information:
We thank many people for helping collect samples. This work was funded by the National Natural Science Foundation of China ( 41571130063 ), the Strategic Priority Research Program of the Chinese Academy of Sciences ( XDB15020302 and XDB15020402 ) and the National Key Research and Development Program of China-International collaborative project from Ministry of Science and Technolog y (Grant No. 2017YFE0107300 ). Authors want to specially thank MS Hui-Ling Cui for helping in developing the graphs.
Publisher Copyright:
© 2019 The Authors
PY - 2019/10
Y1 - 2019/10
N2 - The concept of planetary health acknowledges the links between ecosystems, biodiversity and human health and well-being. Soil, the critical component of the interconnected ecosystem, is the most biodiverse habitat on Earth, and soil microbiomes play a major role in human health and well-being through ecosystem services such as nutrient cycling, pollutant remediation and synthesis of bioactive compounds such as antimicrobials. Soil is also a natural source of antimicrobial resistance, which is often termed intrinsic resistance. However, increasing use and misuse of antimicrobials in humans and animals in recent decades has increased both the diversity and prevalence of antimicrobial resistance in soils, particularly in areas affected by human and animal wastes, such as organic manures and reclaimed wastewater, and also by air transmission. Antimicrobials and antimicrobial resistance are two sides of the sword, while antimicrobials are essential in health care; globally, antimicrobial resistance is jeopardizing the effectiveness of antimicrobial drugs, thus threatening human health. Soil is a crucial pathway through which humans are exposed to antimicrobial resistance determinants, including those harbored by human pathogens. In this review, we use the nexus of antimicrobials and antimicrobial resistance as a focus to discuss the role of soil in planetary health and illustrate the impacts of soil microbiomes on human health and well-being. This review examines the sources and dynamics of antimicrobial resistance in soils and uses the perspective of planetary health to track the movement of antimicrobial-resistance genes between environmental compartments, including soil, water, food and air.
AB - The concept of planetary health acknowledges the links between ecosystems, biodiversity and human health and well-being. Soil, the critical component of the interconnected ecosystem, is the most biodiverse habitat on Earth, and soil microbiomes play a major role in human health and well-being through ecosystem services such as nutrient cycling, pollutant remediation and synthesis of bioactive compounds such as antimicrobials. Soil is also a natural source of antimicrobial resistance, which is often termed intrinsic resistance. However, increasing use and misuse of antimicrobials in humans and animals in recent decades has increased both the diversity and prevalence of antimicrobial resistance in soils, particularly in areas affected by human and animal wastes, such as organic manures and reclaimed wastewater, and also by air transmission. Antimicrobials and antimicrobial resistance are two sides of the sword, while antimicrobials are essential in health care; globally, antimicrobial resistance is jeopardizing the effectiveness of antimicrobial drugs, thus threatening human health. Soil is a crucial pathway through which humans are exposed to antimicrobial resistance determinants, including those harbored by human pathogens. In this review, we use the nexus of antimicrobials and antimicrobial resistance as a focus to discuss the role of soil in planetary health and illustrate the impacts of soil microbiomes on human health and well-being. This review examines the sources and dynamics of antimicrobial resistance in soils and uses the perspective of planetary health to track the movement of antimicrobial-resistance genes between environmental compartments, including soil, water, food and air.
KW - Antimicrobials
KW - Human health
KW - Planetary health
KW - Resistome
KW - Soil microbiome
UR - http://www.scopus.com/inward/record.url?scp=85069803805&partnerID=8YFLogxK
U2 - 10.1016/j.envint.2019.105059
DO - 10.1016/j.envint.2019.105059
M3 - Review article
C2 - 31374443
AN - SCOPUS:85069803805
VL - 131
JO - Environmental International
JF - Environmental International
SN - 0160-4120
M1 - 105059
ER -
