Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

Marc Vendrell; Gaddamanugu Gopi Krishna; Krishna Kanta Ghosh; Duanting Zhai; Jun Seok Lee; Qing Zhu; Yin Hoe Yau; Susana Geifman Shochat; Hyori Kim; Junho Chung; Young Tae Chang

doi:10.1039/c1cc11774b

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

Marc Vendrell, Gaddamanugu Gopi Krishna, Krishna Kanta Ghosh, Duanting Zhai, Jun Seok Lee, Qing Zhu, Yin Hoe Yau, Susana Geifman Shochat, Hyori Kim, Junho Chung, Young Tae Chang

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

Original language	English
Pages (from-to)	8424-8426
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	29
DOIs	https://doi.org/10.1039/c1cc11774b
Publication status	Published - 2011 Aug 7
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.",

author = "Marc Vendrell and Krishna, {Gaddamanugu Gopi} and Ghosh, {Krishna Kanta} and Duanting Zhai and Lee, {Jun Seok} and Qing Zhu and Yau, {Yin Hoe} and Shochat, {Susana Geifman} and Hyori Kim and Junho Chung and Chang, {Young Tae}",

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AU - Vendrell, Marc

AU - Krishna, Gaddamanugu Gopi

AU - Ghosh, Krishna Kanta

AU - Zhai, Duanting

AU - Lee, Jun Seok

AU - Zhu, Qing

AU - Yau, Yin Hoe

AU - Shochat, Susana Geifman

AU - Kim, Hyori

AU - Chung, Junho

AU - Chang, Young Tae

PY - 2011/8/7

Y1 - 2011/8/7

N2 - The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

AB - The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

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U2 - 10.1039/c1cc11774b

DO - 10.1039/c1cc11774b

M3 - Article

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JF - Chemical Communications

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ER -

Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

Abstract

ASJC Scopus subject areas

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