Abstract
A liver transplantation is a treatment option in selected patients with hepatocellular carcinoma (HCC). Despite the adequate selection of candidates, recurrences of HCC may still develop. Solitary extrahepatic metastasis from HCC after a liver transplantation is rare. Here we report two cases of HCC demonstrated extrahepatic recurrence to the adrenal gland and spleen, respectively, within one year after a liver transplantation. Since the treatment of solitary extrahepatic metastasis from HCC after a liver transplantation is not standardized, surgical resection was performed. In the case of HCC adrenal metastasis, innumerable intrahepatic metastases were found two months after the adrenalectomy. And 16 months after adrenalectomy, the patient expired due to tumor progression and hepatic failure. In the case of HCC splenic metastasis, postoperative radiation therapy was performed. However, two recurrent HCC nodules were found 15 months after the splenectomy and received transarterial chemoembolization (TACE). And 29 month after the splenectomy, the patient also expired as same causes of former patient.
| Original language | English |
|---|---|
| Pages (from-to) | 199-203 |
| Number of pages | 5 |
| Journal | Yonsei Medical Journal |
| Volume | 52 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2011 Jan 1 |
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Keywords
- Adrenal metastasis
- Hepatocellular carcinoma
- Liver transplantation
- Splenic metastasis
ASJC Scopus subject areas
- Medicine(all)
Cite this
Solitary extrahepatic intraabdominal metastasis from hepatocellular carcinoma after liver transplantation. / Choi, Sae-Byeol; Kim, Hyungi; Kim, Sung Hoon; Park, Young Nyun; Kim, Kyung Sik.
In: Yonsei Medical Journal, Vol. 52, No. 1, 01.01.2011, p. 199-203.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Solitary extrahepatic intraabdominal metastasis from hepatocellular carcinoma after liver transplantation
AU - Choi, Sae-Byeol
AU - Kim, Hyungi
AU - Kim, Sung Hoon
AU - Park, Young Nyun
AU - Kim, Kyung Sik
PY - 2011/1/1
Y1 - 2011/1/1
N2 - A liver transplantation is a treatment option in selected patients with hepatocellular carcinoma (HCC). Despite the adequate selection of candidates, recurrences of HCC may still develop. Solitary extrahepatic metastasis from HCC after a liver transplantation is rare. Here we report two cases of HCC demonstrated extrahepatic recurrence to the adrenal gland and spleen, respectively, within one year after a liver transplantation. Since the treatment of solitary extrahepatic metastasis from HCC after a liver transplantation is not standardized, surgical resection was performed. In the case of HCC adrenal metastasis, innumerable intrahepatic metastases were found two months after the adrenalectomy. And 16 months after adrenalectomy, the patient expired due to tumor progression and hepatic failure. In the case of HCC splenic metastasis, postoperative radiation therapy was performed. However, two recurrent HCC nodules were found 15 months after the splenectomy and received transarterial chemoembolization (TACE). And 29 month after the splenectomy, the patient also expired as same causes of former patient.
AB - A liver transplantation is a treatment option in selected patients with hepatocellular carcinoma (HCC). Despite the adequate selection of candidates, recurrences of HCC may still develop. Solitary extrahepatic metastasis from HCC after a liver transplantation is rare. Here we report two cases of HCC demonstrated extrahepatic recurrence to the adrenal gland and spleen, respectively, within one year after a liver transplantation. Since the treatment of solitary extrahepatic metastasis from HCC after a liver transplantation is not standardized, surgical resection was performed. In the case of HCC adrenal metastasis, innumerable intrahepatic metastases were found two months after the adrenalectomy. And 16 months after adrenalectomy, the patient expired due to tumor progression and hepatic failure. In the case of HCC splenic metastasis, postoperative radiation therapy was performed. However, two recurrent HCC nodules were found 15 months after the splenectomy and received transarterial chemoembolization (TACE). And 29 month after the splenectomy, the patient also expired as same causes of former patient.
KW - Adrenal metastasis
KW - Hepatocellular carcinoma
KW - Liver transplantation
KW - Splenic metastasis
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U2 - 10.3349/ymj.2011.52.1.199
DO - 10.3349/ymj.2011.52.1.199
M3 - Article
C2 - 21155056
AN - SCOPUS:78650572210
VL - 52
SP - 199
EP - 203
JO - Yonsei Medical Journal
JF - Yonsei Medical Journal
SN - 0513-5796
IS - 1
ER -