Sonography-guided OK-432 sclerotherapy for benign thyroid cysts

Seung Hyun Cho, Seung Hoon Lee, Kwang-Yoon Jung, Jeong-Soo Woo, Seung Kuk Back, Ji Ho Choi, June Choi, Soon Young Kwon

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Conclusion: Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients. Objective: To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts. Patients and methods: The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05). Results: Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3%) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.

Original languageEnglish
Pages (from-to)597-600
Number of pages4
JournalActa Oto-Laryngologica
Volume128
Issue number5
DOIs
Publication statusPublished - 2008 Apr 23

Fingerprint

Picibanil
Sclerotherapy
Cysts
Ultrasonography
Thyroid Gland
Thyroid Nodule
Therapeutics
Morbidity
Injections
Neoplasms

Keywords

  • OK-432
  • Sclerotherapy
  • Thyroid cyst

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Sonography-guided OK-432 sclerotherapy for benign thyroid cysts. / Cho, Seung Hyun; Lee, Seung Hoon; Jung, Kwang-Yoon; Woo, Jeong-Soo; Back, Seung Kuk; Choi, Ji Ho; Choi, June; Kwon, Soon Young.

In: Acta Oto-Laryngologica, Vol. 128, No. 5, 23.04.2008, p. 597-600.

Research output: Contribution to journalReview article

@article{2d7557f11a0548f8bb5d2fbd3be7bc13,
title = "Sonography-guided OK-432 sclerotherapy for benign thyroid cysts",
abstract = "Conclusion: Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients. Objective: To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts. Patients and methods: The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05). Results: Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3{\%}) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.",
keywords = "OK-432, Sclerotherapy, Thyroid cyst",
author = "Cho, {Seung Hyun} and Lee, {Seung Hoon} and Kwang-Yoon Jung and Jeong-Soo Woo and Back, {Seung Kuk} and Choi, {Ji Ho} and June Choi and Kwon, {Soon Young}",
year = "2008",
month = "4",
day = "23",
doi = "10.1080/00016480701635159",
language = "English",
volume = "128",
pages = "597--600",
journal = "Acta Oto-Laryngologica",
issn = "0001-6489",
publisher = "Informa Healthcare",
number = "5",

}

TY - JOUR

T1 - Sonography-guided OK-432 sclerotherapy for benign thyroid cysts

AU - Cho, Seung Hyun

AU - Lee, Seung Hoon

AU - Jung, Kwang-Yoon

AU - Woo, Jeong-Soo

AU - Back, Seung Kuk

AU - Choi, Ji Ho

AU - Choi, June

AU - Kwon, Soon Young

PY - 2008/4/23

Y1 - 2008/4/23

N2 - Conclusion: Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients. Objective: To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts. Patients and methods: The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05). Results: Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3%) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.

AB - Conclusion: Sonography-guided OK-432 sclerotherapy is effective and safe, and offers a useful alternative treatment for benign thyroid cysts in selected patients. Objective: To review the results of sonography guided OK-432 sclerotherapy for benign thyroid cysts. Patients and methods: The details of 20 patients who registered at our institute from December 2002 through August 2006, with recurrent cystic thyroid nodules after two or more aspirations, and who were cytologically negative for malignancy, were reviewed. All cases received OK-432 injections at a concentration of 0.05 mg/ml with sonography. When treatment results were unsatisfactory, the procedure was repeated up to three times at approximately 4 week intervals (mean number, 2.05). Results: Five of the 20 cases were excluded for various reasons. Eleven of the remaining 15 cases (73.3%) showed good responses (<10 mm in diameter), whereas the other 4 patients showed poor responses. All patients tolerated the therapy well, and no significant morbidity or complication occurred among patients treated by OK-432 sclerotherapy.

KW - OK-432

KW - Sclerotherapy

KW - Thyroid cyst

UR - http://www.scopus.com/inward/record.url?scp=42249103096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42249103096&partnerID=8YFLogxK

U2 - 10.1080/00016480701635159

DO - 10.1080/00016480701635159

M3 - Review article

VL - 128

SP - 597

EP - 600

JO - Acta Oto-Laryngologica

JF - Acta Oto-Laryngologica

SN - 0001-6489

IS - 5

ER -