Abstract
DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.
| Original language | English |
|---|---|
| Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 391-392 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806490 |
| Publication status | Published - 2016 |
| Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: 2016 Oct 9 → 2016 Oct 13 |
Other
| Other | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| Country | Ireland |
| City | Dublin |
| Period | 16/10/9 → 16/10/13 |
Keywords
- Dissloved oxygen concentration gradient
- Gas permeability
- Oxygen sensor
ASJC Scopus subject areas
- Control and Systems Engineering
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Cite this
Jang, H., & Lee, S. H. (2016). Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 391-392). Chemical and Biological Microsystems Society.