Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies

Heeyeong Jang, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages391-392
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 92016 Oct 13

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/916/10/13

Keywords

  • Dissloved oxygen concentration gradient
  • Gas permeability
  • Oxygen sensor

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    Jang, H., & Lee, S. H. (2016). Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 391-392). Chemical and Biological Microsystems Society.