Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies

Heeyeong Jang, Sang Hoon Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages391-392
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 92016 Oct 13

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/916/10/13

Fingerprint

Gas supply
Dissolved oxygen
Cell culture
Microfluidics
Stem cells
Scavenging
Gases
Oxygen

Keywords

  • Dissloved oxygen concentration gradient
  • Gas permeability
  • Oxygen sensor

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Jang, H., & Lee, S. H. (2016). Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 391-392). Chemical and Biological Microsystems Society.

Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. / Jang, Heeyeong; Lee, Sang Hoon.

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 391-392.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jang, H & Lee, SH 2016, Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, pp. 391-392, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland, 16/10/9.
Jang H, Lee SH. Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society. 2016. p. 391-392
Jang, Heeyeong ; Lee, Sang Hoon. / Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. pp. 391-392
@inproceedings{72907fc26ece446682a65a8b363b168f,
title = "Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies",
abstract = "DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.",
keywords = "Dissloved oxygen concentration gradient, Gas permeability, Oxygen sensor",
author = "Heeyeong Jang and Lee, {Sang Hoon}",
year = "2016",
language = "English",
pages = "391--392",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",

}

TY - GEN

T1 - Spatiotemporally controlled dissolved oxygen concentration gradient generation inside of microfluidic chip without gas supplies

AU - Jang, Heeyeong

AU - Lee, Sang Hoon

PY - 2016

Y1 - 2016

N2 - DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.

AB - DO concentration is known as one of the important microenvironmental factors during stem cell culture because it can decide the destiny of cell like proliferation or remaining stemness. There are some studies to evaluate the impact of DO concentration during stem cell culture by generating DO concentration gradient inside of microfluidic chip. However, these platforms used additional channel structure with gas or scavenging/producing chemicals to diffuse oxygen through cell culture region. Here, we suggest DO generating method inside of PDMS microfluidic chip without any other components like gas channel or chemicals.

KW - Dissloved oxygen concentration gradient

KW - Gas permeability

KW - Oxygen sensor

UR - http://www.scopus.com/inward/record.url?scp=85014259566&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85014259566&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:85014259566

SP - 391

EP - 392

BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

PB - Chemical and Biological Microsystems Society

ER -