Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning

Hyun Taek Kim, Il Hwan Kim, Kea Joo Lee, Jung Ryun Lee, Soon Kwon Park, Yong Hyuck Chun, Hyun Kim, Im Joo Rhyu

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

New synapse formation may underlie learning and memory. To examine specific synaptic plasticity by motor learning, we conducted quantitative analysis of synapses between parallel fibers and Purkinje cell dendritic spines in cerebella of rats trained to complete various obstacle courses. Synapses between parallel fibers and Purkinje cell spines were classified into single synapse boutons, multiple synapse boutons, and multiple synapse spines by their different contact features, Acrobat-trained animals had more single and multiple synaptic boutons, without change of multiple synapse spines, than motor control animals. These results may suggest that motor learning induces specific synaptogenesis and Purkinje cell spines are primary sites in motor learning-dependent cerebellar synaptic plasticity.

Original languageEnglish
Pages (from-to)1607-1610
Number of pages4
JournalNeuroReport
Volume13
Issue number13
Publication statusPublished - 2002 Sep 16

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Motor Skills
Purkinje Cells
Synapses
Spine
Learning
Neuronal Plasticity
Dendritic Spines
Presynaptic Terminals
Cerebellum

Keywords

  • Dendritic spine
  • Motor learning
  • Parallel fiber
  • Plasticity
  • Purkinje cell
  • Synapse

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Kim, H. T., Kim, I. H., Lee, K. J., Lee, J. R., Park, S. K., Chun, Y. H., ... Rhyu, I. J. (2002). Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning. NeuroReport, 13(13), 1607-1610.

Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning. / Kim, Hyun Taek; Kim, Il Hwan; Lee, Kea Joo; Lee, Jung Ryun; Park, Soon Kwon; Chun, Yong Hyuck; Kim, Hyun; Rhyu, Im Joo.

In: NeuroReport, Vol. 13, No. 13, 16.09.2002, p. 1607-1610.

Research output: Contribution to journalArticle

Kim, HT, Kim, IH, Lee, KJ, Lee, JR, Park, SK, Chun, YH, Kim, H & Rhyu, IJ 2002, 'Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning', NeuroReport, vol. 13, no. 13, pp. 1607-1610.
Kim HT, Kim IH, Lee KJ, Lee JR, Park SK, Chun YH et al. Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning. NeuroReport. 2002 Sep 16;13(13):1607-1610.
Kim, Hyun Taek ; Kim, Il Hwan ; Lee, Kea Joo ; Lee, Jung Ryun ; Park, Soon Kwon ; Chun, Yong Hyuck ; Kim, Hyun ; Rhyu, Im Joo. / Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning. In: NeuroReport. 2002 ; Vol. 13, No. 13. pp. 1607-1610.
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