Spinal cord injury after conducting transcatheter arterial chemoembolization for costal metastasis of hepatocellular carcinoma.

Sang Jung Park, Chang Ha Kim, Jin Dong Kim, Soon-Ho Um, Sun Young Yim, Min Ho Seo, Dae In Lee, Jun Hyuk Kang, Bora Keum, Yong Sik Kim

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Transcatheter arterial chemoembolization (TACE) has been used widely to treat patients with unresectable hepatocellular carcinoma. However, this method can induce various adverse events caused by necrosis of the tumor itself or damage to nontumor tissues. In particular, neurologic side effects such as cerebral infarction and paraplegia, although rare, may cause severe sequelae and permanent disability. Detailed information regarding the treatment process and prognosis associated with this procedure is not yet available. We experienced a case of paraplegia that occurred after conducting TACE through the intercostal artery to treat hepatocellular carcinoma that had metastasized to the rib. In this case, TACE was attempted to relieve severe bone pain, which had persisted even after palliative radiotherapy. A sudden impairment of sensory and motor functions after TACE developed in the trunk below the level of the sternum and in both lower extremities. The patient subsequently received steroid pulse therapy along with supportive care and continuous rehabilitation. At the time of discharge the patient had recovered sufficiently to enable him to walk by himself, although some paresthesia and spasticity remained.

Original languageEnglish
Pages (from-to)316-320
Number of pages5
JournalClinical and molecular hepatology
Volume18
Issue number3
Publication statusPublished - 2012 Sep 1
Externally publishedYes

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Paraplegia
Spinal Cord Injuries
Hepatocellular Carcinoma
Neoplasm Metastasis
Sternum
Paresthesia
Patient Discharge
Cerebral Infarction
Ribs
Nervous System
Lower Extremity
Necrosis
Radiotherapy
Rehabilitation
Arteries
Steroids
Bone and Bones
Pain
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Spinal cord injury after conducting transcatheter arterial chemoembolization for costal metastasis of hepatocellular carcinoma. / Park, Sang Jung; Kim, Chang Ha; Kim, Jin Dong; Um, Soon-Ho; Yim, Sun Young; Seo, Min Ho; Lee, Dae In; Kang, Jun Hyuk; Keum, Bora; Kim, Yong Sik.

In: Clinical and molecular hepatology, Vol. 18, No. 3, 01.09.2012, p. 316-320.

Research output: Contribution to journalArticle

Park, Sang Jung ; Kim, Chang Ha ; Kim, Jin Dong ; Um, Soon-Ho ; Yim, Sun Young ; Seo, Min Ho ; Lee, Dae In ; Kang, Jun Hyuk ; Keum, Bora ; Kim, Yong Sik. / Spinal cord injury after conducting transcatheter arterial chemoembolization for costal metastasis of hepatocellular carcinoma. In: Clinical and molecular hepatology. 2012 ; Vol. 18, No. 3. pp. 316-320.
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