Spontaneously healed asymptomatic pulmonary tuberculosis

Prevalence of airflow obstruction, and correlation between high-resolution CT findings and pulmonary function tests

Ki Yeol Lee, Chol Shin, Jung Bok Lee, Eun-Young Kang, Yu Whan Oh, Bo-Kyung Je, Ji Young Choo, Dae Wui Yoon, Pyong Kon Cho

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2 Citations (Scopus)

Abstract

RATIONALE AND OBJECTIVES: We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings. MATERIALS AND METHODS: We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB. RESULTS: The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema. CONCLUSION: The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.

Original languageEnglish
Pages (from-to)528-533
Number of pages6
JournalJournal of Computer Assisted Tomography
Volume36
Issue number5
DOIs
Publication statusPublished - 2012 Sep 1

Fingerprint

Respiratory Function Tests
Pulmonary Tuberculosis
Tomography
Emphysema
Interferons
Thorax
Lung

Keywords

  • airway obstruction
  • computed tomography
  • prevalence
  • respiratory function test
  • tomography
  • tuberculosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Spontaneously healed asymptomatic pulmonary tuberculosis: Prevalence of airflow obstruction, and correlation between high-resolution CT findings and pulmonary function tests",
abstract = "RATIONALE AND OBJECTIVES: We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings. MATERIALS AND METHODS: We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB. RESULTS: The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4{\%} [11/82]) than those with normal CXR (7.4{\%} [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema. CONCLUSION: The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.",
keywords = "airway obstruction, computed tomography, prevalence, respiratory function test, tomography, tuberculosis",
author = "Lee, {Ki Yeol} and Chol Shin and Lee, {Jung Bok} and Eun-Young Kang and Oh, {Yu Whan} and Bo-Kyung Je and Choo, {Ji Young} and Yoon, {Dae Wui} and Cho, {Pyong Kon}",
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T1 - Spontaneously healed asymptomatic pulmonary tuberculosis

T2 - Prevalence of airflow obstruction, and correlation between high-resolution CT findings and pulmonary function tests

AU - Lee, Ki Yeol

AU - Shin, Chol

AU - Lee, Jung Bok

AU - Kang, Eun-Young

AU - Oh, Yu Whan

AU - Je, Bo-Kyung

AU - Choo, Ji Young

AU - Yoon, Dae Wui

AU - Cho, Pyong Kon

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N2 - RATIONALE AND OBJECTIVES: We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings. MATERIALS AND METHODS: We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB. RESULTS: The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema. CONCLUSION: The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.

AB - RATIONALE AND OBJECTIVES: We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings. MATERIALS AND METHODS: We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB. RESULTS: The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema. CONCLUSION: The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.

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