Spread of nontuberculous mycobacteria from 1993 to 2006 in Koreans

Weon Ryoo Sung, Sonya Shin, Myung Shup Shim, Yoon Sung Park, Jin Lew Woo, Sue Nie Park, Kil Park Young, Seong Man Kang

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

In Korea, the prevalence of nontuberculous mycobacterial (NTM) pulmonary disease has risen, observed primarily in immunocompetent patients with or without preexisting lung disease. The purpose of this study was to determine the frequency of various species of NTM isolates from respiratory specimens in a single institution over a 14-year period in Korea. All samples referred to our reference laboratory over a 14-year period in Korea were analyzed. From 1993 to 2000 our laboratory used conventional NTM identification methods, and from 2001 we adapted PCR-restriction fragment length polymorphism analysis (PRA). A total of 17,915 isolates were collected from 1993 to 2006. The most frequently isolated organisms were M. avium complex (n = 11,705, 65%), M. abscessus (n = 2,076, 11.59%), M. fortuitum complex (n = 1,279, 7.14%). M. chelonae complex (n = 1,134, 6.33%), M. kansasii (n = 762, 4.25%), M. szulgai (n = 139, 0.78%), M. celatum (n = 87, 0.49%), M. scrofulaceum (n = 18, 0.10%) and M. marium (n = 11, 0.06%).

Original languageEnglish
Pages (from-to)415-420
Number of pages6
JournalJournal of Clinical Laboratory Analysis
Volume22
Issue number6
DOIs
Publication statusPublished - 2008 Dec 1

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Keywords

  • Identification
  • Nontuberculous mycobacteria (NTM)
  • PCR-restriction fragment length polymorphism (PRA)

ASJC Scopus subject areas

  • Medical Laboratory Technology
  • Microbiology (medical)
  • Immunology and Allergy
  • Hematology
  • Public Health, Environmental and Occupational Health
  • Biochemistry, medical
  • Clinical Biochemistry

Cite this

Sung, W. R., Shin, S., Shim, M. S., Park, Y. S., Woo, J. L., Park, S. N., Young, K. P., & Kang, S. M. (2008). Spread of nontuberculous mycobacteria from 1993 to 2006 in Koreans. Journal of Clinical Laboratory Analysis, 22(6), 415-420. https://doi.org/10.1002/jcla.20278