STABILIZED1 as a heat stress-specific splicing factor in Arabidopsis thaliana

Geun Don Kim, Sang-Dong Yoo, Young Hee Cho

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To overcome high temperature stress, plants have developed transcriptional cascades which express a large amount of chaperone proteins called heat shock proteins (HSPs). In our recent publication, we reported that STABILIZED1, as an U5-snRNP-interacting protein, is involved in the splicing of heat shock factor (HSF) and HSP transcripts during high temperature stress. This indicates that not only transcriptional regulation, but also post-transcriptional regulation by STA1, is essential for the full activation of HSF-HSP cascades and for thermotolerance. Here, we observed that the splicing of HSP transcripts was induced independent of STA1 at room temperature after heat acclimation, indicating that STA1 acts as a high temperature-specific splicing factor for the splicing of HSP transcripts. Our findings suggest the molecular mechanism for how HSF and HSP transcripts are spliced well under high temperature stress that blocks the splicing of overall transcripts.

Original languageEnglish
Article numbere1432955
JournalPlant Signaling and Behavior
Volume13
Issue number2
DOIs
Publication statusPublished - 2018 Feb 1

Fingerprint

heat shock proteins
heat stress
Arabidopsis thaliana
temperature
plant stress
heat tolerance
acclimation
ambient temperature
proteins
heat

Keywords

  • Heat shock proteins
  • heat stress
  • pre-mRNA splicing
  • STABLIZED1
  • thermotolerance

ASJC Scopus subject areas

  • Plant Science

Cite this

STABILIZED1 as a heat stress-specific splicing factor in Arabidopsis thaliana. / Kim, Geun Don; Yoo, Sang-Dong; Cho, Young Hee.

In: Plant Signaling and Behavior, Vol. 13, No. 2, e1432955, 01.02.2018.

Research output: Contribution to journalArticle

@article{7c922166846e4cc094ff714d6f59dcb7,
title = "STABILIZED1 as a heat stress-specific splicing factor in Arabidopsis thaliana",
abstract = "To overcome high temperature stress, plants have developed transcriptional cascades which express a large amount of chaperone proteins called heat shock proteins (HSPs). In our recent publication, we reported that STABILIZED1, as an U5-snRNP-interacting protein, is involved in the splicing of heat shock factor (HSF) and HSP transcripts during high temperature stress. This indicates that not only transcriptional regulation, but also post-transcriptional regulation by STA1, is essential for the full activation of HSF-HSP cascades and for thermotolerance. Here, we observed that the splicing of HSP transcripts was induced independent of STA1 at room temperature after heat acclimation, indicating that STA1 acts as a high temperature-specific splicing factor for the splicing of HSP transcripts. Our findings suggest the molecular mechanism for how HSF and HSP transcripts are spliced well under high temperature stress that blocks the splicing of overall transcripts.",
keywords = "Heat shock proteins, heat stress, pre-mRNA splicing, STABLIZED1, thermotolerance",
author = "Kim, {Geun Don} and Sang-Dong Yoo and Cho, {Young Hee}",
year = "2018",
month = "2",
day = "1",
doi = "10.1080/15592324.2018.1432955",
language = "English",
volume = "13",
journal = "Plant Signaling and Behavior",
issn = "1559-2316",
publisher = "Landes Bioscience",
number = "2",

}

TY - JOUR

T1 - STABILIZED1 as a heat stress-specific splicing factor in Arabidopsis thaliana

AU - Kim, Geun Don

AU - Yoo, Sang-Dong

AU - Cho, Young Hee

PY - 2018/2/1

Y1 - 2018/2/1

N2 - To overcome high temperature stress, plants have developed transcriptional cascades which express a large amount of chaperone proteins called heat shock proteins (HSPs). In our recent publication, we reported that STABILIZED1, as an U5-snRNP-interacting protein, is involved in the splicing of heat shock factor (HSF) and HSP transcripts during high temperature stress. This indicates that not only transcriptional regulation, but also post-transcriptional regulation by STA1, is essential for the full activation of HSF-HSP cascades and for thermotolerance. Here, we observed that the splicing of HSP transcripts was induced independent of STA1 at room temperature after heat acclimation, indicating that STA1 acts as a high temperature-specific splicing factor for the splicing of HSP transcripts. Our findings suggest the molecular mechanism for how HSF and HSP transcripts are spliced well under high temperature stress that blocks the splicing of overall transcripts.

AB - To overcome high temperature stress, plants have developed transcriptional cascades which express a large amount of chaperone proteins called heat shock proteins (HSPs). In our recent publication, we reported that STABILIZED1, as an U5-snRNP-interacting protein, is involved in the splicing of heat shock factor (HSF) and HSP transcripts during high temperature stress. This indicates that not only transcriptional regulation, but also post-transcriptional regulation by STA1, is essential for the full activation of HSF-HSP cascades and for thermotolerance. Here, we observed that the splicing of HSP transcripts was induced independent of STA1 at room temperature after heat acclimation, indicating that STA1 acts as a high temperature-specific splicing factor for the splicing of HSP transcripts. Our findings suggest the molecular mechanism for how HSF and HSP transcripts are spliced well under high temperature stress that blocks the splicing of overall transcripts.

KW - Heat shock proteins

KW - heat stress

KW - pre-mRNA splicing

KW - STABLIZED1

KW - thermotolerance

UR - http://www.scopus.com/inward/record.url?scp=85042209011&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85042209011&partnerID=8YFLogxK

U2 - 10.1080/15592324.2018.1432955

DO - 10.1080/15592324.2018.1432955

M3 - Article

C2 - 29381447

AN - SCOPUS:85042209011

VL - 13

JO - Plant Signaling and Behavior

JF - Plant Signaling and Behavior

SN - 1559-2316

IS - 2

M1 - e1432955

ER -