Stereoselectivity in the condensation reactions between malate enolate and imines to 2-pyrrolidinone derivatives

Deok Chan Ha, Kyeong Soon Yun, Hye Sang Park, Won Keun Choung, Young Eun Kwon

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Enolate dianion of diethyl (S)-malate was stereoselectively condensed with nonenoiizable N-arylimines to give 2-pyrrolidinone derivatives. The presence of HMPA changes the diastereoselectivity of this cyclization reaction.

Original languageEnglish
Pages (from-to)8445-8448
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number46
DOIs
Publication statusPublished - 1995 Nov 13

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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