Stereoselectivity in the condensation reactions between malate enolate and imines to 2-pyrrolidinone derivatives

Deok-Chan Ha; Kyeong Soon Yun; Hye Sang Park; Won Keun Choung; Young Eun Kwon

doi:10.1016/0040-4039(95)01818-3

Stereoselectivity in the condensation reactions between malate enolate and imines to 2-pyrrolidinone derivatives

Deok-Chan Ha, Kyeong Soon Yun, Hye Sang Park, Won Keun Choung, Young Eun Kwon

College of Science

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

Enolate dianion of diethyl (S)-malate was stereoselectively condensed with nonenoiizable N-arylimines to give 2-pyrrolidinone derivatives. The presence of HMPA changes the diastereoselectivity of this cyclization reaction.

Original language	English
Pages (from-to)	8445-8448
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	46
DOIs	https://doi.org/10.1016/0040-4039(95)01818-3
Publication status	Published - 1995 Nov 13

ASJC Scopus subject areas

Drug Discovery
Organic Chemistry
Biochemistry

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Ha, D-C., Yun, K. S., Park, H. S., Choung, W. K., & Kwon, Y. E. (1995). Stereoselectivity in the condensation reactions between malate enolate and imines to 2-pyrrolidinone derivatives. Tetrahedron Letters, 36(46), 8445-8448. https://doi.org/10.1016/0040-4039(95)01818-3

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abstract = "Enolate dianion of diethyl (S)-malate was stereoselectively condensed with nonenoiizable N-arylimines to give 2-pyrrolidinone derivatives. The presence of HMPA changes the diastereoselectivity of this cyclization reaction.",

author = "Deok-Chan Ha and Yun, {Kyeong Soon} and Park, {Hye Sang} and Choung, {Won Keun} and Kwon, {Young Eun}",

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AU - Choung, Won Keun

AU - Kwon, Young Eun

PY - 1995/11/13

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