Stereospecific ring expansion of β-lactams to γ-lactams with trimethylsilyldiazomethane

Deok Chan Ha; Seogshin Kang; Coo Min Chung; Hyun Kyung Lim

doi:10.1016/S0040-4039(98)01640-2

Stereospecific ring expansion of β-lactams to γ-lactams with trimethylsilyldiazomethane

Deok Chan Ha, Seogshin Kang, Coo Min Chung, Hyun Kyung Lim

College of Science

Research output: Contribution to journal › Article

19 Citations (Scopus)

Abstract

Ring opening of N-carboxylated β-lactams with trimethylsilyldiazomethane anion followed by photolytic Wolff rearrangement provided γ-lactams in a stereospecific manner.

Original language	English
Pages (from-to)	7541-7544
Number of pages	4
Journal	Tetrahedron Letters
Volume	39
Issue number	41
DOIs	https://doi.org/10.1016/S0040-4039(98)01640-2
Publication status	Published - 1998 Oct 8

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Keywords

Azetidinones
Pyrrolidinones
Rearrangements
Ring-transformations

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Ha, D. C., Kang, S., Chung, C. M., & Lim, H. K. (1998). Stereospecific ring expansion of β-lactams to γ-lactams with trimethylsilyldiazomethane. Tetrahedron Letters, 39(41), 7541-7544. https://doi.org/10.1016/S0040-4039(98)01640-2

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Access to Document

10.1016/S0040-4039(98)01640-2