Stereotactic Body Radiotherapy for Centrally Located Primary Non–Small-Cell Lung Cancer: A Meta-Analysis

Tosol Yu, In Soo Shin, Won Sup Yoon, Chai Hong Rim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The feasibility of stereotactic body radiotherapy (SBRT) for centrally located tumors is controversial. SBRT with 100 Gy or higher biologically equivalent dose using an α/β of 10 Gy for centrally located primary NSCLC offered excellent local control (3years; 77.6% [95% confidential interval, 65.2-86.5]), comparable with that of other SBRT reports for peripheral lung tumors. The pooled rate of Grade ≥3 complications was 12.0%. This suggest that SBRT can be used in inoperable centrally located lung tumors with a curative intent.

Original languageEnglish
JournalClinical Lung Cancer
DOIs
Publication statusPublished - 2019 Jan 1

Keywords

  • Dose fractionation
  • Network meta-analysis
  • Non–small-cell lung carcinoma
  • Radiosurgery
  • Survival rate

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

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