Stimuli-responsive polymers in nanotechnology

Deposition and possible effect on drug release

Alexander Yarin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Stimuli-responsive polymers result in on-demand regulation of properties and functioning of various nanoscale systems. In particular, they allow stimuli-responsive control of flow rates through membranes and nanofluidic devices with submicron channel sizes. They also allow regulation of drug release from nanoparticles and nanofibers in response to temperature or pH variation in the surrounding medium. In the present work two relevant mathematical models are introduced to address precipitation-driven deposition of surface layers of stimuli-responsive polymers and describe a possible effect of swelling-shrinkage transition of such polymers on drug release.

Original languageEnglish
Pages (from-to)1-15
Number of pages15
JournalMathematical Modelling of Natural Phenomena
Volume3
Issue number5
DOIs
Publication statusPublished - 2008 Jan 1
Externally publishedYes

Fingerprint

Nanotechnology
Drugs
Polymers
Nanofluidics
Nanofibers
Swelling
Shrinkage
Flow Rate
Nanoparticles
Membrane
Flow rate
Mathematical Model
Mathematical models
Membranes
Temperature

Keywords

  • drug release
  • fluid and solid mechanics
  • polymer deposition
  • probability theory
  • Stimuli-responsive polymers

ASJC Scopus subject areas

  • Modelling and Simulation

Cite this

Stimuli-responsive polymers in nanotechnology : Deposition and possible effect on drug release. / Yarin, Alexander.

In: Mathematical Modelling of Natural Phenomena, Vol. 3, No. 5, 01.01.2008, p. 1-15.

Research output: Contribution to journalArticle

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